Now showing items 1-3 of 3
Methylene tetrahydrofolate reductase and methionine synthase gene polymorphisms as genetic determinants of pre-eclampsia.
BACKGROUND:Pre-eclampsia(PE)isaleadingcauseofmaternalandneonatalmortalityinAfrica;andhasbeen associatedwiththeinterplayofgenetic,metabolicandenvironmentalfactors.Polymorphismsofmethylenetetrahydrofolatereductase(MTHFR)an ...
Epigenetic Modification in Methylene Tetrahydrofolate Reductase (MTHFR) Gene of Women with Pre‑eclampsia
(The Journal of Obstetrics and Gynecology of India, 2020)
Background Genetic and epigenetic factors play significant roles in the aetio-pathogenesis of pre-eclampsia (PE). The effects may vary across racial and geographical boundaries. The role of epigenetic modification in ...
Methylene tetrahydrofolate Reductase Enzyme Level and Antioxidant Activity in Women with Gestational Hypertension and Pre-eclampsia in Lagos, Nigeria.
(The Journal of Obstetrics and Gynecology of India, 2019-04-16)
Background Deficiencies of enzymes in the folate cycle may lead to the generation of homocysteine, a toxic metabolic intermediate with pro-oxidant effect and ability to induce oxidant stress and lipid peroxidation as part ...