Susceptibility of carciogenic steptococcus mutans to extracts of garcinia hibiscus sabdariffa, and solanum americanum
BACKGROUND: The elirnination of cariogenic bacteria from the oral cavity using antibacterial agents is one of the primary strategies for the prevention of dental caries.A variety of plants with potent activity are known to be used in indigenous communities for dental hygiene worldwide. OBJECTIVE: To determine if Hibiscus sabdariffa, Solamon americanum and Garcinia kola can inhibit the growth of cariogenic bacteria in the mouth. METHODS: Methanol and aqueous extracts obtained from three plants, Hibiscus sabdariffa, Solanum americanum and Garciuia kola were studied for their antibacterial activity against .cariogenic Streptococcus mutans obtained from patients with clinically identified carious lesions, using the agar dilution method. The sources of extracts for Garcinia, Hibiscus and Solanum were respectively fruits and leaves for the latter two. RESULTS: The extracts(both methanol and aqueous) from Garcinia kola showed the most intensive activity and completely inhibited the growth of the primary cariogenic Streptococcus mutans at 1.25 mg/ml. Hibiscus sabdarijfa was also active at a minimum inhibitory concentration (MIC) of 2.Smg/ml ,while solanum americanum did not show any direct effect on S. mutans. CONCLUSION: The result of this study showed that G kola and H. sabdariffa have direct antibacterial effect on Streptococcus mutans. WAJM 2008; 27(4): 230-233.
Susceptibility , Cariogenesis , Streptococuus mutans , Garcinia kola , Hibiscus sabdariffa , Sotanum americanum , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Afolabi, O.C, Ogunsola, F.T. and Coker, A.O. (2008). Susceptibility of Cariogenic Streptococcus mutans to extracts of Garcinia kola, Hibiscus sabdariffa, and Solanum americanum. West African Journal of Medicine; 27(4): 230-233.