Department of Radiation Biology, Radiotherapy & Radiodiagnosis

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Browsing Department of Radiation Biology, Radiotherapy & Radiodiagnosis by Subject "Liver tumor"

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    Open Access
    Evaluation of the performance of designed coaxial antennas for hyperthermia using simulation and experimental methods
    (Sciendo, 2021-03-31) Ibitoye, AZ; Ogese, CO; Adedokun, MB; Habeebu, MYM; Nwoye, EO; Aweda, MA
    Introduction: Antenna geometries and tissue properties affect microwave energy distributions during microwave ablation procedures. There is a paucity of information on the potential of antenna fabricated from a thick semi-rigid coaxialcable in the field of microwave thermal therapy. This study aimed at comparing the performance of two dual-slotantennas designed from different semi-rigid coaxial cables for the ablation of a liver tumour using numerical simulationand experimental validation methods. Materials and Methods: COMSOL Multiphysics software was used for designing dual-slot antennas and as well as toevaluate microwave energy deposition and heat distribution in the liver tissue. Experimental validations were conductedon the ex-vivo bovine livers to validate the simulation results. Results: Thick antenna developed in this study produced a higher sphericity index, larger ablation diameter and reducedbackward heating along the antenna shaft than the existing one. The experimental validation results also indicatesignificant differences between the two antennas in terms of ablation diameters (p = 0.04), ablation lengths (p = 0.02)and aspect ratios (p = 0.02). Conclusion: Based on the findings in this study, an antenna fabricated from a thick coaxial cable has ahigher potential oflocalizing microwave energy in the liver than conventional antennas.