Department of Medicine

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Browsing Department of Medicine by Subject "Adolescence"

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    Open Access
    Obesity, family history of diabetes and adolescent type 2 diabetes mellitus - A case report
    (Endocrinology and metabolism society of Nigeria, 2016-09) Ogunwale, O.O; Iwuala, S.O; Odeniyi, I.A; Fasanmade, O.A
    Background: Type 2 diabetes mellitus has been on the rise amongst children and adolescents over the last two decades. Obesity and a family history of diabetes are the most common factors associated with this trend. Objective: To present a case report of type 2 diabetes in an overweight teenager with a strong family history of diabetes mellitus. Method: We describe a case of type 2 diabetes who presented with progressive weight loss, polyuria and polydipsia. We also discuss the results of investigations done, treatment modalities involved and management outcomes. Results: A 14-year-old boy who was dehydrated, had diabetic ketoacidosis, with evidence of chronic hyperglycaemia, and residual pancreatic beta-cell function on investigation. Treatment included prompt rehydration, dietary therapy and a high total daily dose of insulin to achieve glycaemic control over two weeks on admission. He was discharged and subsequently had a progressive reduction in total daily insulin dose due to tight glycaemic control. Treatment was changed to metformin and continued lifestyle modification with which he maintained good glycaemic control. Conclusion: Overweight and obese Nigerian adolescents with a strong family history of diabetes can develop type 2 diabetes mellitus. Lifestyle modification is essential to achieve and maintain good glycaemic control in adolescents with type 2 diabetes.