To determine the prevalence of metabolic syndrome in patients on first visit to diabetic clinic in a tertiary hospital in Lagos, and to compare the prevalence of metabolic syndrome using IDF and NCEP criteria
Loading...
Date
2009
Authors
Kayode, O.O
Dolapo, D.C
Olopade, O.B
Fasanmade, O.A
Ohwovoriole, A.E
Journal Title
Journal ISSN
Volume Title
Publisher
International diabetes federation
Abstract
To determine the prevalence of metabolic syndrome in patients on the first visit to the diabetic clinic in a tertiary hospital in Lagos, and to compare the prevalence of metabolic syndrome using IDF and NCEP criteria.
The case files of patients referred from other health facilities and presenting for the first time in Lagos University Teaching Hospital diabetic clinic seen over the last 2 years January 2007- January 2009 were randomly selected and reviewed. Out of over 500 case files that were reviewed only 150 that had complete data were selected.
The variables that were recorded include age, gender, waist circumference, triglycerides (TG) high-density lipoprotein (HDL), blood pressure and fasting plasma glucose.
currently, two major definitions for metabolic syndrome are provided by the International Diabetes Federation and the revised National Cholesterol Education Program.
The IDF criteria that were used central obesity: waist circumference ≥ 94 cm (male), ≥ 80 cm (female) and any 2 of the following
• dyslipidaemia: TG ≥ 1.7 mmol/L (150 mg/dl) or specific treatment
• dyslipidaemia: HDL-C < 40 mg/dL (male), < 50 mg/dL (female)
• blood pressure ≥ 130/85 mmHg or previously diagnosed
• fasting plasma glucose ≥ 5.6 mmol/L (100 mg/dl or previously diagnosed
• For the US National Cholesterol Education Program Adult Treatment Panel III NCEP requires at least three of the following:
• central obesity: waist circumference ≥ 102 cm or 40 inches (male), ≥ 88 cm or 36 inches(female)
• dyslipidaemia: TG ≥ 1.695 mmol/L (150 mg/dl)
• dyslipidaemia: HDL-C < 40 mg/dL (male), < 50 mg/dL (female)
• blood pressure ≥ 130/85 mmHg
• fasting plasma glucose ≥ 6.1 mmol/L (110 mg/dl)
Results
Characteristics of the study participants Table 1
Variable Frequency Percent
Age (years)
<30 1 0.7
30-39 11 7.5
40-49 28 19.0
50-59 41 27.9
60-69 52 35.4
70-79 14 9.5
Total 147 100
Sex
Male 74 50.3
Female 73 49.7
Total 147 100
Duration of diabetes
<1month 22 15.0
1 month to 1 year 29 19.7
>1 year to 3 years 32 21.8
>3 years to 5 years 12 8.2
>5 years 52 35.4
Total 147 100
Body Mass Index (BMI)
<20 5 3.4
20-24.9 46 31.3
25-29.9 58 39.5
≥30 38 25.9
Total 147 100
Mean age = 56.0 ± 10.8 year
Mean duration of diabetes = 58.8 ± 62.7 months
PREVALENCE OF METABOLIC SYNDROME
Metabolic Syndrome (IDF)
Sex Present Absent Total
Male 20 (27.03)% 54 (72.93%) 74
Female 47 (64.38%) 26 (35.62%) 73
Total 67 80 147
Metabolic Syndrome (NCEP)
Sex Present Absent Total
Male 19 (25.68)% 55 (74.32%) 74
Female 43 (58.90%) 30 (41.10%) 73
Total 62 85 147
The prevalence of metabolic syndrome using IDF criteria was 67 (45.6%) out of 147 patients -20 males and 47 females. Using the NCEP it was 62 (42.2%) 19 males and 43 females.
The IDF was able to pick more patients with Metabolic syndrome than the NCEP and this was a statistically significant p-value = 0.000 X2 46.08
The prevalence was higher in females. This was statistically significant p-value = 0.00001(IDF) and p-value =0.00004. The reasons for this need to be further studied.
There is an association between BMI and Metabolic syndrome p-value =0.00
There was no correlation between age and Metabolic syndrome p-value =0.85. There was no correlation between duration of diabetes and Metabolic syndrome p-value =0.98
discussion/conclusion
Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. It affects one in five people, and prevalence increases with age. The prevalence of metabolic syndrome in this study using IDF criteria was 67 (45.6%) out of 147 patients -20 males and 47 females. Using the NCEP it was 62 (42.2%) 19 males and 43 females. This is much higher than expected but not surprising as the study was carried out amongst diabetics.
It was found out that the metabolic syndrome was more prevalent among females than males. The IDF was able to pick more patients with Metabolic syndrome than the NCEP.
Description
Conference papers
Keywords
Metabolic syndrome , Diabetic clinic , Patients , Health facilities , Research Subject Categories::MEDICINE
Citation
Kayode OO, Dolapo DC, Olopade OB, Fasanmade OA, Ohwovoriole AE. To determine the prevalence of metabolic syndrome in patients on first visit to diabetic clinic in a tertiary hospital in Lagos, and to compare the prevalence of metabolic syndrome using IDF and NCEP criteria. International Diabetes Federation congress, Montreal, Canada 2009