A five year review of ovarian cancer at a tertiary institution in Lagos, South West, Nigeria

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Okunade, KS
Okunola, H
Okunowo, AA
Anorlu, RI
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Background: Ovarian cancer constituted 7% of gynecological malignancies seen in Lagos, Nigeria and was the second most common cause of death among women in Lagos, Nigeria. Objectives: The aim is to determine the prevalence of ovarian cancer and characteristics of patients with ovarian cancer at a Tertiary Institution in Lagos. Patients and Methods: This was a retrospective review of all the patients with histologically confirmed ovarian cancer admitted to the gynecological ward of the hospital over a period of 5 years. Relevant information was extracted from the ward register and patients medical case records. Data were analyzed using Epi‑info statistical software package and results were then presented in tables and chart. Results: Fifty cases of ovarian cancer were admitted during the period under review. This constituted 1.7% of the gynecological admission cases and 8.2% of the gynecological malignancies managed in the hospital during the study. It was the second most common gynecological malignancy. The mean age of the ovarian cancer patients was 45.7 ± 4.3 years with the majority of the patients (58%) being premenopausal, 34% being nulliparous and only 16% having one or more risk factors. The abdominal swelling was the most common presenting symptom with 80% of the patients presenting with advanced disease. Epithelial ovarian cancer was the most common histological variant. The most common treatment modality was surgery and chemotherapy. The patient default rate was 64%. Conclusion: Ovarian cancer cases are on the increase. Failure of optimal management is worsened by the delay in presentation and poor compliance to treatment with high patients’ default rate.
Scholarly articles
Epithelial , Lagos , Ovarian cancer , Prevalence , Research Subject Categories::PHARMACY
Okunade KS, Okunola H, Okunowo AA, Anorlu RI. A five year review of ovarian cancer at a tertiary institution in Lagos, South West, Nigeria. Niger J Gen Pract 2016; 14(2): 23-7.