Are systemic antibiotics necessary in the prevention of wound healing complications after intra-alveolar dental extraction?

dc.contributor.authorGbotolorun, O M
dc.contributor.authorDipo-Fagbemi, I M
dc.contributor.authorOlojede, A O
dc.contributor.authorEbigwe, S
dc.contributor.authorAdetoye, J O
dc.date.accessioned2019-09-11T14:39:59Z
dc.date.available2019-09-11T14:39:59Z
dc.date.issued2016
dc.descriptionStaff publicationsen_US
dc.description.abstractThis double-blind, randomized controlled study was done to assess the necessity of systemic antibiotics in the prevention of wound healing complications after intra-alveolar dental extraction. A consecutive recruitment method was used to allocate participants to two treatment groups. Subjects in group A (antibiotics group, n = 75) received amoxicillin and metronidazole for 5 days postoperatively, while those in group B (placebo group, n = 75) were given identical-looking placebo drugs in place of the antibiotics. Postoperative socket healing complications, pain, and compliance with postoperative instructions were assessed postoperatively. Healing was uneventful in 129 patients (86%). Twenty-one patients (14%) developed wound healing complications. Dry socket was the most common complication in the antibiotics group (six subjects), while acutely inflamed sockets was the most common in the placebo group (five subjects). Non-adherence to postoperative instructions and postoperative pain were found to be significantly associated with the development of wound healing complications. The prescription of antibiotics after routine intra-alveolar dental extraction in healthy patients may not play any significant role in preventing wound healing complications. However, non-compliance with postoperative instructions might be associated with increased wound healing complicationen_US
dc.identifier.citationGbotolorun, O.M. [Et...al] (2016). Are systemic antibiotics necessary in the prevention of wound healing complications after intra-alveolar dental extraction?.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/5494
dc.language.isoenen_US
dc.publisherInt J Oral Maxillofac Surg.en_US
dc.subjectAntibiotics useen_US
dc.subjectIntra-alveolar dental extractionen_US
dc.titleAre systemic antibiotics necessary in the prevention of wound healing complications after intra-alveolar dental extraction?en_US
dc.typeArticleen_US
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