Investigation of the antioxidant properties of Chrysophyllum albidum leaves

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Adeshina Y.O.
Ayoola G.A.
Adegoke A.O.
Adepoju-Bello, A.A.
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Nigerian Journal of Health and Biomedical Sciences
Chrysophyllum albidum G Don, Sapotaceae is an indigenous plant in traditional medicine of West africa used for fever, stomach ache, diarrhea and wound healing. The present study was evaluate the phytochemical and antioxidant properties of Chrysophyllum albidum (leaves). The.plant extract was tested for DPPH (1, 1-diphenyl-2-picryl hyrazyl) radical scavenging activity, iron.chelating activity, total phenolic, total flavonoid, proanthocyanidin and total iron content. The leaves tested positive to alkaloids, flavonoids, glycosides, saponins, iron, fixed oils and reducing sugars but.tested negative for the presence of volatile oils, anthracene glycosides, deoxy pentose and keto sugars. The IC50 values were {20 μg/m!, 23 μg/ml for DPPH activity in the order {Vitamin C, Extract} while the IC50 values for the iron chelating activity were {16 μg/ml, indeterminate} in the order of {NaEDTA, Extract}. The total phenolic content, total flavonoid content, and proanthocyanidin contents are 1058 mg, 669 mg, and 353.7 mg; as gallic acid, rutin and catechin equivalents per 100 qrams of the leaves respectively. The total iron content was 2.82 mg/g of the leaves extract. The results obtained in the present study indicate that extracts of C. albidum leaves are potential sources of natural antioxidants.
Scholarly articles
Antioxidant , Radicals , Flavonoid , Phenolic content , Research Subject Categories::PHARMACY , Research Subject Categories::PHARMACY::Pharmaceutical chemistry
Adeshina YO, Ayoola GA, Adepoju-Bello AA, Adegoke AO, (2011). Investigation of the Antioxidant properties of Chrysophyllum albidum leaves. Nigerian Journal of Health and Biomedical Sciences, 10 (1): 45-49.