Bio-accessibility based risk assessment of PAHs in soils from sites of different anthropogenic activities in Lagos, Nigeria using the Fed Organic Estimation Human Simulation Test method

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dc.contributor.authorAdetunde, O. T.
dc.contributor.authorMills, G. A.
dc.contributor.authorOlayinka, K. O.
dc.contributor.authorAlo, B. I.
dc.date.accessioned2019-08-27T15:25:38Z
dc.date.available2019-08-27T15:25:38Z
dc.date.issued2018-07-12
dc.description.abstractThe aim of this study was to carry out a bio-accessibility based risk assessment of polycyclic aromatic hydrocarbon (PAHs) in soils from sites of different anthropogenic activities in Lagos, Nigeria. Using an in vitro gastrointestinal model – Fed Organic Estimation Human Simulation Test method (FOREShT)), the concentration of bio-accessible 16 priority US Environmental Protection Agency (USEPA) PAHs in soils were determined. Total concentration of 16 priority USEPA PAHs was also determined. The concentration range was 702 to 253,922 ng g-1 and 92-760 ng g-1 for total and bio-accessible PAHs respectively. For persons involved with activities at these sites no health risk were observed, based on bio-accessibility values of PAHs. Mean daily intake of PAHs from these soils were below the oral mean daily intake threshold for PAHs in food. Also, overall estimated theoretical cancer risk (2.5 × 10-09, 6.5 × 10-07, 5.5 × 10-10, 2.7 × 10-09, 6.5 × 10-10, 9.5 × 10-10, 2.0 × 10-09 and 4.1 × 10-07 for the eight sites based on their bio-accessible concentration) for exposure to PAHs in surface soils were below the health guidelines for extreme (1 × 10-04) and normal (1 × 10-06) exposures.en_US
dc.identifier.citationAdetunde, O. T., Mills, G. A., Olayinka, K. O., & Alo, B. I. (2018). Bioaccessibility-based risk assessment of PAHs in soils from sites of different anthropogenic activities in Lagos, Nigeria using the fed organic estimation human simulation test method. Soil and Sediment Contamination: An International Journal, 27(6), 501-512.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/4791
dc.language.isoenen_US
dc.publisherTaylor and Francisen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCES::Chemistry::Analytical chemistry::Separation methodsen_US
dc.subjectBio-accessibilityen_US
dc.subjectPolycyclic Aromatic Hydrocarbonsen_US
dc.subjectRisk assessmenten_US
dc.subjectFed Organic Estimation Human Simulation Test methoden_US
dc.titleBio-accessibility based risk assessment of PAHs in soils from sites of different anthropogenic activities in Lagos, Nigeria using the Fed Organic Estimation Human Simulation Test methoden_US
dc.typeArticleen_US
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