Substituent effect on spectral and antimicrobial activity of Schiff bases derived from aminobenzoic acids

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dc.contributor.authorEjiah, F.N.
dc.contributor.authorFasina, T.M.
dc.contributor.authorFamiloni, O.B.
dc.contributor.authorOgunsola, F.T.
dc.date.accessioned2019-08-29T13:41:02Z
dc.date.available2019-08-29T13:41:02Z
dc.date.issued2013-10-02
dc.descriptionStaff Publicationsen_US
dc.description.abstractThe dependence of electronic absorption spectra an- timicrobial property on the substituent position was investigated using three Schiff bases derived from salicylaldehyde and isomeric aminobenzoic acids in three solvents of different polarities. The absorption maxima in all three solvents exhibited dependence on the position of substituent with the absorption maxima undergoing a red shift as solvent polarity increased. The in vitro antibacterial activity of the compounds against some clinically important bacteria namely Es- cherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Staphylococcus aureus (ATCC 25923), Enterococcus feacalis (ATCC 29212) was determined in N,N”-dimethylformamide and 1,4-dioxane using the agar dilution method. The results revealed that the ortho and meta substituted Schiff bases exhibited better antimicrobial activity in the non-polar solvent.en_US
dc.identifier.citationEjiah, F. N., Fasina, T. M., Familoni, O. B., & Ogunsola, F. T. (2013). Substituent effect on spectral and antimicrobial activity of Schiff bases derived from aminobenzoic acids. Advances in Biological Chemistry, Vol.3(05), 475pp.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/4885
dc.language.isoenen_US
dc.publisherresearchgate.neten_US
dc.relation.ispartofseriesAdvances in Biological Chemistry;Vol.3(5)
dc.subjectResearch Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry::Bioorganic chemistryen_US
dc.subjectSchiff Baseen_US
dc.subjectAminobenzoic Aciden_US
dc.subjectantibacterial activityivityen_US
dc.subjectSalicyaldehydeen_US
dc.subjectElectronic Spectraen_US
dc.titleSubstituent effect on spectral and antimicrobial activity of Schiff bases derived from aminobenzoic acidsen_US
dc.typeArticleen_US
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