Screening of Some Medicinal Plants Used in South-West Nigerian Traditional Medicine for Anti-Salmonella typhi Activity

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dc.contributor.authorAkinyemi, K.O.
dc.contributor.authorMendie, U.E.
dc.contributor.authorSmith, S.T.
dc.contributor.authorOyefolu, A.O.
dc.contributor.authorCoker, A.O.
dc.date.accessioned2022-09-09T14:33:17Z
dc.date.available2022-09-09T14:33:17Z
dc.date.issued2009-08-20
dc.descriptionScholarly articleen_US
dc.description.abstractTen Nigerian medicinal plants used traditionally for the treatment of several ailments of both microbial and non-microbial origins were tested on multi-drug resistant S. typhi(MDR) strains of which six of them were active. The results revealed that both the aqueous and ethanol extracts of Terminalia avicennioides, Momordica balsamina, Combretum paniculatum and Trema guineensis were effective on the MDR-S. typhi strains with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values ranging from 9.60 to 14 mcg/ml and 24 to 33 mcg/ml, respectively. Whereas, only the aqueous extracts of Morinda Ocimum gratissimum were found to be active against this pathogen with MIC and MBC values of 9.60 and 24 mcg/ml for M. lucida, 40 and 55 mcg/ml for O. gratissimum, respectively. There was no statistical significant difference (P > 0.05) between the activity of each plant extract and the decoctions prepared from them. All the six active plants showed positive reactions to alkaloids, tannins, flavonoids and anthraquinones but in variable degrees. All but M. balsamina, indicated the presence of saponin.en_US
dc.identifier.citationK. O. Akinyemi, U. E. Mendie, S. T. Smith, A. O. Oyefolu & A. O. Coker (2005) Screening of Some Medicinal Plants Used in South-West Nigerian Traditional Medicine for Anti-Salmonella typhi Activity, Journal of Herbal Pharmacotherapy, 5:1, 45-60, DOI: 10.1080/J157v05n01_06en_US
dc.identifier.otherDOI: 10.1080/J157v05n01_06
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/11398
dc.language.isoenen_US
dc.publisherTaylor & Francis Online(Journal of Herbal Pharmacotherapy)en_US
dc.subjecterbal medicine extracts susceptibilityen_US
dc.subjectminimum inhibitory concentrationsen_US
dc.subjectphotochemicalen_US
dc.subjectmulti-drugs resistanten_US
dc.subjectSalmonella typhien_US
dc.subjectTyphoid Feveren_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleScreening of Some Medicinal Plants Used in South-West Nigerian Traditional Medicine for Anti-Salmonella typhi Activityen_US
dc.typeArticleen_US
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