Antibiotic susceptibility of common bacterial pathogens in urinary tract infections in a Teaching hospital in Southwestern Nigeria

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dc.contributor.authoroluremi, B.B.
dc.contributor.authorIdowu, A.O.
dc.contributor.authorOlaniyi, J.F.
dc.date.accessioned2022-01-10T09:44:04Z
dc.date.available2022-01-10T09:44:04Z
dc.date.issued2011-10-16
dc.descriptionScholarly articlesen_US
dc.description.abstractUrinary tract infection (UTI) is one of the most common bacterial infections in humans and a major cause of morbidity. However, the aetiology of UTI and their antibiotic sensitivity patterns vary from time to time and across different areas. This study determines the frequently isolated UTI bacteria from inpatients and out-patients of a Teaching hospital in Southwestern Nigeria and their antibiotic susceptibility patterns. Sixty (60) bacterial isolates from urine of patients with significant bacteriuria in UTI were collected and evaluated for their antibiotic sensitivity using modified Kirby-Bauer method. UTI was frequently encountered in females (61.7%) and older patients (50%). 55% of the isolates were from in-patients. The most common etiological organisms of UTI were Esherichia coli (46.7%), Pseudomonas aeruginosa (18.3%), Klebsiella spp (13.3%), Staphylococcus aureus (13.3%) and Proteus spp (6.7%). Pseudomonas aeruginosa was found only among hospital isolates while Staphylococcus aureus was isolated from females only. Antibiotic susceptibility pattern revealed that the Enterobacteriaceae were highly susceptible to Ciprofloxacin (71.4 to 75%) while Nitrofurantoin demonstrated the best activity against S. aureus isolates (100%) in both community and hospital-acquired UTI. All the isolates exhibited a high degree of resistance to Augmentin and amoxicillin. A high rate of multi-drug resistance was recorded among all isolates. In view of the increasing rate of resistance of UTI pathogens to commonly used antibiotics, rational prescription and use of antibiotics is advocateden_US
dc.identifier.citationOluremi BB,Idowu AO,Olaniyi JF.Antibiotic susceptibility of common bacterial pathogens in Urinary Tract infections in a Teaching Hospital in Southwestern Nigeria. African Journal of Microbiological Research (2011)5(22):3658-3663en_US
dc.identifier.issn1996-0808
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/10057
dc.language.isoenen_US
dc.publisherAfrican Journal of Microbiological Researchen_US
dc.subjectUrinary tract infectionsen_US
dc.subjectBacterial pathogensen_US
dc.subjectSusceptibilityen_US
dc.subjectMorbidityen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleAntibiotic susceptibility of common bacterial pathogens in urinary tract infections in a Teaching hospital in Southwestern Nigeriaen_US
dc.typeArticleen_US
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