Aeropalynology and Allergenicity of Pollen in Selected Locations Within Lagos Metropolis, Nigeria

dc.contributor.authorAdeniyi, T.A
dc.date.accessioned2018-09-28T13:20:00Z
dc.date.available2018-09-28T13:20:00Z
dc.date.issued2017-12
dc.descriptionUniversity of Lagos School of Postgraduate Studies Phd Thesis and Dissertationen_US
dc.description.abstractAirborne pollen grains and fern spores (aeroflora) are some of the major causative agents of allergies. However, data gathering on composition and distribution of these aeroflora across Nigeria is incipient. The aim of this study is to monitor the aeroflora in Lagos metropolis and determine the allergenicity of dominant aeroflora. To achieve this, aerosampling was done in Surulere, Ebute-Metta, University of Lagos, Akoka (UNILAG), Bariga and Gbagada. Aerosamples were collected and analysed monthly from January, 2013 to December, 2014. Aeroflora were identified and data obtained was correlated with weather parameters and allergy cases. Dominant aeroflora were freshly collected and their proteins were extracted and subjected to allergenicity tests. A total of 5174 pollen grains and 323 fern spores were collected in all the selected locations in 2013 while 4769 pollen grains and 488 fern spores were collected in the same locations in 2014. Dominant pollen grains recorded were those of Alchornea cordifolia, family Amaranthaceae, Casuarina equisetifolia, family Cyperaceae, family Poaceae, and Terminalia catappa. Pollen and spores counts (PSC) in Surulere, Ebute-Metta and Bariga showed significant negative correlation with relative humidity (p ≤ 0.05). PSC in UNILAG and Gbagada showed significant positive correlation with wheezing cough (p ≤ 0.05). Allergenicity tests revealed a total of 14 allergenic proteins, whereby 12 were newly identified. Results showed that individuals were most susceptible to the 58 kDa allergenic protein of Alchornea cordifolia pollen (84 %; 42 individuals). In conclusion, the general public can now be informed and educated on occurrence and frequency of aeroflora in the studied areas which will assist allergy sufferers in managing allergies. Furthermore, allergenic proteins identified can be used to develop immunotherapy drugs and aid allergy diagnosis, and treatment in Nigeria.en_US
dc.identifier.citationAdeniyi, T.A (2017) Aeropalynology and Allergenicity of Pollen in Selected Locations Within Lagos Metropolis, Nigeria. University of Lagos School of Postgraduate Studies Phd Thesis and Dissertationen_US
dc.identifier.other060803005 DECEMBER
dc.identifier.urihttp://ir.unilag.edu.ng:8080/xmlui/handle/123456789/3165
dc.language.isoenen_US
dc.subjectAllergenic proteinsen_US
dc.subjectFern sporesen_US
dc.subjectAllergiesen_US
dc.subjectPollen grainsen_US
dc.titleAeropalynology and Allergenicity of Pollen in Selected Locations Within Lagos Metropolis, Nigeriaen_US
dc.typeThesisen_US
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