Correlation between Wayne’s Score and Laboratory Evidence of Thyrotoxicosis in Nigeria

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Sabir, A.A
Iwuala, S.O
Fasanmade, O.A
Abubakar, S.A
Haruna, G.Y
Ohwovoriole, A.E
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Background: The diagnosis of thyrotoxicosis is based on clinical suspicion and confirmed by thyroid function test. In Nigeria, measurements of thyroid function tests are not readily available therefore the need for clinical assessment remains paramount in the diagnosis and management of thyrotoxicosis. Objective: The objective was to determine the relationship between Wayne’s score and biochemical indices of thyroid function in Nigerians. Materials and Methods: A total of 30 newly diagnosed patients with thyrotoxicosis referred to the Endocrinology Clinic were recruited for participation in this study. All patients had detailed history taken and thorough physical examinations performed. They were also assessed using the Wayne’s score. The patients also had the biochemical evaluation of their thyroid function. The relationship between the Wayne’s score values and the biochemical indices were then correlated using the Pearson’s correlation coefficient. Results: All the patients with elevated thyroid hormones had elevated Wayne’s score. The correlation coefficient between T3 and Wayne’s score was 0.79, whereas between T4 and Wayne’s score was 0.81. The average Wayne’s score was 31.6. There was negative correlation between age and Wayne’s score (r = −0.86).Conclusion: The Wayne’s score can be used as a screening tool for thyrotoxicosis in our environment.
Thyroid hormones, thyrotoxicosis, Wayne’s score
Sabir AA, Iwuala SO, Fasanmade OA, Abubakar SA, Haruna GY, Ohwovoriole AE. Correlation between Wayne’s Score and Laboratory Evidence of Thyrotoxicosis in Nigeria. Sub-Saharan African Journal of Medicine. 2014; 1(3):142-144