Antimicrobial activity of the essential oil and the fractional samples obtained from the leaves and seeds of Phyllanthus amarus (Euphorbiaceae)
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The aim of this study is to investigate the alleged antimicrobial activity of P. amarus. Fresh leaves and seeds of the plant were air-dried, pulverized and the essential oil extracted into hexane by hydrodistillation over a period of 4 h. In addition, hourly fractions were collected and sensitivity tests were carried out on twelve microorganisms including yeast, Gram-positive and Gram-negative bacteria. All the samples of essential oil and fractions demonstrated activity against the microorganisms except Pseudomonas aeruginosa. The activity of the essential oil collected over 4 h exceeded that of the control 0.05% ciprofloxacin, for Staphylococcus aureus (isolate) and Bacillus subtilis. The results indicate the use of the plant as an antimicrobial. Thus, there is scientific basis for the use of the plant in the treatment of bacterial and fungal diseases.
Research Subject Categories::NATURAL SCIENCES::Chemistry::Analytical chemistry::Electrochemistry
Ogunlesi, M., Okiei, W., Osibote, E. A. S., & Muotoh, C. (2009). Antimicrobial activity of the essential oil and the fractional samples obtained from the leaves and seeds of Phyllanthus amarus (Euphorbiaceae). Research Journal of Phytochemistry, 3(4), 77-84.