Comparison of the Minimental State Examination Scale and the International HIV Dementia Scale in Assessing Cognitive Function in Nigerian HIV Patients on Antiretroviral Therapy.

Simple item page
dc.contributor.authorOshinaike, O.O.
dc.contributor.authorAkinbami, A.A.
dc.contributor.authorOjo, O.O.
dc.contributor.authorOjini, F.I.
dc.contributor.authorOkubadejo, N.U.
dc.contributor.authorDanesi, M.A.
dc.date.accessioned2019-11-04T08:14:27Z
dc.date.available2019-11-04T08:14:27Z
dc.date.issued2012-09-25
dc.descriptionStaff publicationsen_US
dc.description.abstractINTRODUCTION: HIV-associated neurocognitive disorder (HAND) remains common despite the availability of antiretroviral therapy. Routine screening will improve early detections. OBJECTIVE: To compare the performance of the minimental state examination (MMSE) and international HIV dementia scale (IHDS) in assessing neurocognitive function in HIV/AIDS patients on antiretroviral therapy. METHODS: A case-control study of 208 HIV-positive and 121 HIV-negative individuals. Baseline demographic data were documented and cognitive function assessed using the two instruments. CD4 cell counts were recorded. RESULTS: Cases comprised 137 females and 71 males. Controls were 86 females and 35 males. Mean MMSE score of cases was 27.7 ± 1.8 compared to 27.8 ± 1.3 in controls (P = 0.54). Mean IHDS score in cases was 8.36 ± 3.1 compared to 10.7 ± 0.9 in controls (P < 0.001). Using the MMSE scale, 6 cases but no controls had HAND (P = 0.09). Using the IHDS, 113 (54.3%) had HAND compared with 10 (8.3%) controls (P < 0.0001). Using IHDS, 56.5% cases with CD4 count > 200 had HAND compared with 92.5% with CD4 count < 200 (P < 0.001). CONCLUSION: These findings indicate that the IHDS detects higher rates of HAND and may identify HIV/AIDS patients who require further cognitive assessment using more robust assessment batteries.en_US
dc.identifier.citationOshinaike OO, Akinbami AA, Ojo OO, Ojini IF, Okubadejo UN, Danesi AM. Comparison of the Minimental State Examination Scale and the International HIV Dementia Scale in Assessing Cognitive Function in Nigerian HIV Patients on Antiretroviral Therapy. AIDS Res Treat. 2012;2012:581531.en_US
dc.identifier.otherdoi: 10.1155/2012/581531.
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6715
dc.language.isoenen_US
dc.publisherHindawien_US
dc.subjectHIV/AIDSen_US
dc.subjectCognitive dysfunctionen_US
dc.subjectInternational HIV dementia scaleen_US
dc.subjectMini mental State Examinationen_US
dc.subjectNeurologyen_US
dc.subjectHIV associated neurocognitive deficit (HAND)en_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleComparison of the Minimental State Examination Scale and the International HIV Dementia Scale in Assessing Cognitive Function in Nigerian HIV Patients on Antiretroviral Therapy.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Oshinaike OO et al. Comparison of MMSE and IHDS in HIV AIDS.pdf
Size:
570.39 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medicine- Scholarly Publications