Presenting Symptoms and Predictors of Poor Outcomes Among 2,184 Patients with COVID-19 in Lagos State, Nigeria.

dc.contributor.authorAbayomi, A
dc.contributor.authorOdukoya, O
dc.contributor.authorOsibogun, A
dc.contributor.authorWright, O
dc.contributor.authorAdebayo, B
dc.contributor.authorBalogun, M
dc.date.accessioned2022-09-02T14:26:08Z
dc.date.available2022-09-02T14:26:08Z
dc.date.issued2020
dc.descriptionScholarly articleen_US
dc.description.abstractIntroduction: Lagos state remains the epicentre of COVID-19 in Nigeria. We describe the symptoms and signs of the first 2,184 PCR-confirmed COVID-19 patients admitted at COVID-19 treatment centers in Lagos State. We also assessed the relationship between patients’ presenting symptoms, sociodemographic and clinical characteristics and COVID-19 deaths. Methods: Medical records of PCR-confirmed COVID-19 patients were extracted and analyzed for their symptoms, symptom severity, presence of comorbidities and outcome. Results: The ages of the patients ranged from4 days to 98 years with a mean of43.0(16.0)years.Of the patients who presented with symptoms, cough(19.3%) was the most common presenting symptom. This was followed by fever (13.7%) and difficulty in breathing, (10.9%). The most significant clinical predictor of death was the severity of symptoms and signs at presentation. Difficulty in breathing was the most significant symptom predictor of COVID-19 death (OR:19.26 95% CI 10.95-33.88). The case fatality rate was 4.3%. Conclusion: Primary care physicians and COVID-19 frontline workers should maintain a high index of suspicion and prioritize the care of patients presenting with these symptoms. Community members should be educated on such predictors and ensure that patients with these symptoms seek care early to reduce the risk of deaths associated with COVID-19.en_US
dc.description.sponsorshipLagos State Governmenten_US
dc.identifier.citationAbayomi A, Odukoya O, Osibogun A, Wright O, Adebayo B, Balogun M et al. Presenting Symptoms and Predictors of Poor Outcomes Among 2,184 Patients with COVID-19 in Lagos State, Nigeria. Int J Infect Dis. 2020 Oct 16:S1201-9712(20)32228-1. doi: 10.1016/j.ijid.2020.10.024.en_US
dc.identifier.otherdoi: 10.1016/j.ijid.2020.10.024
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/11265
dc.language.isoenen_US
dc.publisherInt J Infect Disen_US
dc.subjectCOVID-19 Symptomsen_US
dc.subjectCOVID-19 deathsen_US
dc.subjectPatientsen_US
dc.subjectResearch Subject Categories::MEDICINE::Social medicineen_US
dc.titlePresenting Symptoms and Predictors of Poor Outcomes Among 2,184 Patients with COVID-19 in Lagos State, Nigeria.en_US
dc.typeArticleen_US
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