Histopathological Effect of Cypermethrin on Juvenile African Catfish (Clarias gariepinus)

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Ayoola, S. O.
Ajani, E.K
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The acute toxicity of cypermethrin an insecticide, to juvenile African catfish, C. gariepinus was investigated with emphasis on histopathological effects. Clarias gariepinus (Burchell 1822) juvenile were exposed to 0, 1.9, 4.1, 9, 21, and 45mg/l of cypermethrin. The lethal concentration (LC50) value of cypermethrin was 0.063mg/l for 96h of exposure. The mean mortality percentages were 0, 0, 70, 90, 100 and 100, in the order of concentration of 0, 1.9, 4.1, 9, 21 and 45 mg/L respectively. Cypermethin concentration corresponding to the 96h LC50 value for juvenile C. gariepinus was used to study the effects of cypermethin exposures in inducing histopathological changes of gills, liver, kidney and brain. In the gills, filament cell proliferation, cellular infiltration, haemorrhage and epithelial lifting were observed. In the liver, there was vacuolation of hepatocytes and necrosis. In kidney there was exfoliation and swollen with pyknotic nuclei. The brain showed neuronal degeneration and spongiosis. These changes occurred predominantly in the 96h exposure. Respiratory stress, erratic swimming and instant death of fish were observed in exposed fish, which varies with the concentration of the toxicant and it’s showed that mortality increased with increase in concentration. Cypermethrin is highly toxic to juvenile fish.
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Clarias gariepinus , Acute toxicity , Histopathology , Cypermethrin , Research Subject Categories::NATURAL SCIENCES
Ayoola, S.O. and Ajani, E.K. (2008). Histopathological Effect of Cypermethrin on Juvenile African Catfish (Clarias gariepinus). World Journal of Biological Research. Vol.1(2): 1-14.