Genotoxicity Evaluation of Landfill Solid Leachates from Waste Dumpsite in Lagos State, Nigeria Using the Allium cepa Assay

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dc.contributor.authorOgunyemi, A.K
dc.contributor.authorSamuel, A.T
dc.contributor.authorAmund, O.O
dc.contributor.authorIlori, M.O
dc.date.accessioned2019-06-17T15:11:59Z
dc.date.available2019-06-17T15:11:59Z
dc.date.issued2018
dc.descriptionStaff publicationsen_US
dc.description.abstractThe management of municipal landfill’s leachate is considered one of the most significant environmental issues. Potential mutagenic and genotoxic effects of solid waste leachates (SWL) were investigated using the Allium cepa root meristematic cells assay technique. In Allium root growth inhibition test, experimental onion bulbs were cultivated in various concentrations of the SWL and distilled water was used as a negative control. The root tips from the treated bulb were processed by orcein squash technique after 72 h. The mean lengths of root bundles were obtained and effective concentration (EC) values calculated. Some of the physico chemical properties of the WL were also determined. The A. cepa assay was carried out at concentrations of 0.05, 0.1, 2.0, 5, 10, 20, 50 and 100% of the WL. There was a statistically different (p < 0.05), concentration dependent inhibition of onion root growth and mitotic index, and induction of chromosomal aberrations in the onion test. The results of the physicochemical analysis revealed that the concentrations of some parameters were above the maximum permissible limit set by the world health organization (WHO) and could partly be correlated with the toxicity of wastewater. The landfill leachates pose a risk to human health and the environment in general. Hence, ecotoxicity/ genotoxicity assays would be useful in leachate risk assessment when coupled with physicochemical analysis.en_US
dc.identifier.citationOgunyemi, A.K [Et...al] (2018). Genotoxicity Evaluation of Landfill Solid Leachates from Waste Dumpsite in Lagos State, Nigeria Using the Allium cepa Assay. Plant and Animal Research Journal, Vol.1(3), 68-76pp.en_US
dc.identifier.uridoi: 10.11594/parj.01.03.02
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/4180
dc.language.isoenen_US
dc.relation.ispartofseriesPlant and Animal Research Journal;Vol.1 (3)
dc.subjectGenotoxicityen_US
dc.subjectChromosomal aberrationen_US
dc.subjectSolid waste leachatesen_US
dc.subjectMitotic indexen_US
dc.subjectAllium cepaen_US
dc.subjectResearch Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases::Microbiologyen_US
dc.titleGenotoxicity Evaluation of Landfill Solid Leachates from Waste Dumpsite in Lagos State, Nigeria Using the Allium cepa Assayen_US
dc.typeArticleen_US
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