Effects of coating the powder on the tensile strength, disintegration and dissolution of lactose tablets
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Date
1983
Authors
Igwilo, C.I
Pilpel, N
Journal Title
Journal ISSN
Volume Title
Publisher
lnternational Journal of Pharmaceutics
Abstract
A study has been made of the effects produced on the tensile strength, disintegration and dissolution of lactose tablets by coating the powder with increasing amounts of paraffins.
Addition of paraffins reduces the tensile strength and prolongs the disintegration and dissolution times. Silicones produce similar effects on the disintegration times. The disintegration and dissolution results have been explained in terms of the changes produced by the coatings on the wettability of the powder.
Description
Keywords
tensile strength , disintegration , dissolution , lactose tablets , powder coating
Citation
Igwilo, C.I. and Pilpel, N. (1983). Effects of coating the powder on the tensile strength, disintegration and dissolution of lactose tablets. lnternational Journal of Pharmaceutics, 15, 73-85