Evaluation of the Antibacterial activity of Herbal ointments formulated with Methanolic extract of Cassia alata

Simple item page
dc.contributor.authorAlalor, C.
dc.contributor.authorIgwilo, C.I.
dc.contributor.authorAzubuike, C.P.
dc.date.accessioned2020-02-24T11:02:58Z
dc.date.available2020-02-24T11:02:58Z
dc.date.issued2012
dc.descriptionStaff publicationsen_US
dc.description.abstractIn this study, the antibacterial potency of herbal ointments formulated with methanolic extract of Cassia alata was evaluated. The preliminary in vitro antibacterial activity of the methanolic extracts of sun-dried leaves of Cassia alata was determined against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa using the Agar cup plate method. The antibacterial activity of the extract was predominantly against Gram-positive organisms. Herbal ointments were prepared by incorporating the methanolic extract of Cassia alata (10 % w/w) into aqueous cream, emulsifying ointment and simple ointment bases and evaluated for their in vitro antibacterial efficacy. The formulation containing Cassia alata extract in aqueous cream showed comparatively better antibacterial activity than the other formulations in the following order: aqueous cream > emulsifying ointment > simple ointment > crude extract. The herbal ointment also compared favourably with a commercial brand of Gentamicin ointment. This study shows that Cassia alata has antibacterial activity and also has high potential as antibacterial agent when formulated as ointment for topical use and could therefore explain the successes claimed in the folk use of the plant in the treatment of common skin conditionsen_US
dc.identifier.citationAlalor C. A., Igwilo C. I., Azubuike C. P. (2012). Evaluation of the Antibacterial activity of Herbal ointments formulated with Methanolic extract of Cassia alata. Asian Journal of Biomedical & Pharmaceutical Sciences, 2(13), 15-19.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7822
dc.language.isoenen_US
dc.publisherAurangabad : Literati Scientific and Publishersen_US
dc.relation.ispartofseriesAsian Journal of Biomedical & Pharmaceutical Sciences;Vol.2(13)
dc.subjectCassia alataen_US
dc.subjectAntibacterial propertiesen_US
dc.subjectBacillus subtilisen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectEscherichia colien_US
dc.subjectPseudomonas aeruginosaen_US
dc.subjectHerbal ointmentsen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleEvaluation of the Antibacterial activity of Herbal ointments formulated with Methanolic extract of Cassia alataen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Article 10.pdf
Size:
543.43 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Pharmaceutics and Pharmaceutical Technology- Scholarly Publications