A continuous quality improvement strategy to strengthen screening practices and facilitate the routine use of intravenous iron for treating anaemia in pregnant and postpartum women in Nigeria: a study protocol

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dc.contributor.authorEboreime, E.
dc.contributor.authorThomas, A.B
dc.contributor.authorObi-Cheff, C.
dc.contributor.authorAdelabu, Y
dc.contributor.authorBalogun, M
dc.contributor.authorAiyenigba, A.A
dc.contributor.authorOluwole, E.O.
dc.contributor.authorAkinajo, O.R
dc.contributor.authorAfolabi, B.B.
dc.date.accessioned2023-06-02T14:28:38Z
dc.date.available2023-06-02T14:28:38Z
dc.date.issued2023
dc.descriptionScholarly article
dc.description.abstractBackground Pregnancy-related anaemia is a public health challenge across Africa. Over 50% of pregnant women in Africa get diagnosed with this condition, and up to 75% of these are caused by iron deficiency. The condition is a significant contributor to the high maternal deaths across the continent and, in particular, Nigeria, which accounts for about 34% of global maternal deaths. Whereas oral iron is the mainstay treatment for pregnancy-related anaemia in Nigeria, this treatment is not very effective given the slow absorption of the medication, and its gastrointestinal adverse effects which lead to poor compliance by women. Intravenous iron is an alternative therapy which can rapidly replenish iron stores, but fears of anaphylactic reactions, as well as several misconceptions, have inhibited its routine use. Newer and safer intravenous iron formulations, such as ferric carboxymaltose, present an opportunity to overcome some concerns relating to adherence. Routine use of this formulation will, however, require addressing misconceptions and systemic barriers to adoption in the continuum of care of obstetric women from screening to treatment. This study aims to test the options to strengthen routine screening for anaemia during and immediately after pregnancy, as well as evaluate and improve conditions necessary to deliver ferric carboxymaltose to pregnant and postpartum women with moderate to severe anaemia. Methods This study will be conducted in a cluster of six health facilities in Lagos State, Nigeria. The study will employ continuous quality improvement through the Diagnose-Intervene-Verify-Adjust framework and Tanahashi’s model for health system evaluation to identify and improve systemic bottlenecks to the adoption and implementation of the intervention. Participatory Action Research will be employed to engage health system actors, health services users, and other stakeholders to facilitate change. Evaluation will be guided by the consolidated framework for implementation research and the normalisation process theory. Discussion We expect the study to evolve transferable knowledge on barriers and facilitators to the routine use of intravenous iron that will inform scale-up across Nigeria, as well as the adoption of the intervention and strategies inother countries across Africa.
dc.description.sponsorshipThis work was supported, in whole or in part, by the Bill & Melinda Gates Foundation [INV-032486]. Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned
dc.identifier.citationA continuous quality improvement strategy to strengthen screening practices and facilitate the routine use of intravenous iron for treating anaemia in pregnant and postpartum women in Nigeria: a study protocol
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/12461
dc.titleA continuous quality improvement strategy to strengthen screening practices and facilitate the routine use of intravenous iron for treating anaemia in pregnant and postpartum women in Nigeria: a study protocol
dc.typeArticle
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