Type 2 diabetes complications and comorbidity in Sub-Saharan Africans

Simple item page
dc.contributor.authorEkoru, K
dc.contributor.authorDoumatey, A
dc.contributor.authorBentley, A.R
dc.contributor.authorChen, G
dc.contributor.authorZhou, J
dc.contributor.authorShriner, D
dc.contributor.authorFasanmade, O
dc.date.accessioned2019-12-20T11:15:12Z
dc.date.available2019-12-20T11:15:12Z
dc.date.issued2019-10
dc.description.abstractBackground: Context-specific evidence of the spectrum of type 2 diabetes (T2D) burden is essential for setting priorities and designing interventions to reduce associated morbidity and mortality. However, there are currently limited data on the burden of T2D complications and comorbidity in sub-Saharan Africa (SSA). METHODS: T2D complications and comorbidities were assessed in 2,784 participants with diabetes enrolled from tertiary health centres and contextualised in 3,209 individuals without diabetes in Nigeria, Ghana and Kenya. T2D complications and comorbidities evaluated included cardiometabolic, ocular, neurological and renal characteristics. FINDINGS: The most common complications/comorbidities among the T2D participants were hypertension (71%; 95% CI 69-73), hyperlipidaemia (34%; 95% CI 32-36), and obesity (27%; 95% CI 25-29). Additionally, the prevalence of cataracts was 32% (95% CI 30-35), diabetic retinopathy 15% (95% CI 13-17), impaired renal function 13% (95% CI 12-15), and erectile dysfunction (in men) 35% (95% CI 32-38). T2D population-attributable fraction for these comorbidities ranged between 6 and 64%. INTERPRETATION: The burden of diabetes complications and comorbidity is substantial in SSA highlighting the urgent need for innovative public health strategies that prioritise promotion of healthy lifestyles for prevention and early detection of T2D. Also needed are strategies to strengthen health care system capacities to provide treatment and care for diabetes complicationsen_US
dc.identifier.citationEkoru K, Doumatey A, Bentley AR, Chen G, Zhou J, Shriner D, Fasanmade O, Okafor G, Eghan B Jr, Agyenim-Boateng K, Adeleye J, Balogun W, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C, Collins F, Dunston G, Adeyemo A, Rotimi C. Type 2 diabetes complications and comorbidity in Sub-Saharan Africans. EClinicalMedicine. 2019 Oct 17;16:30-41. doi: 10.1016/j.eclinm.2019.09.001. eCollection 2019 Noven_US
dc.identifier.issn25898-5370
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7194
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectCo-morbidity; Complications; Epidemiology; Sub-Sahara Africa; Type 2 Diabetesen_US
dc.titleType 2 diabetes complications and comorbidity in Sub-Saharan Africansen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Type 2 diabetes complications and comorbidity in Sub-Saharan Africans - EClinicalMedicine.pdf
Size:
526.47 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medicine- Scholarly Publications