Physicochemical and microbiological evaluation of acid modified native starch derived from Borassus aethiopum (Arecaceae) shoot

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dc.contributor.authorAzubuike, C.P.
dc.contributor.authorAdeluola, A.O.
dc.contributor.authorMgboko, M.S.
dc.contributor.authorMadu, S.J.
dc.date.accessioned2020-02-24T11:30:32Z
dc.date.available2020-02-24T11:30:32Z
dc.date.issued2018-05
dc.descriptionStaff publicationsen_US
dc.description.abstractPurpose: To evaluate the physicochemical properties and microbiological quality of Borassus aethiopum shoot acid-modified starch (AMS) for potential pharmaceutical applications. Methods: Modification of Borassus aethiopum native starch (NS) was carried out using 6 % w/v HCl at 37 ± 2 oC for 192 h. The AMS was characterised for their morphological, micromeritics, rheological, thermal properties as well as their microbiological quality using standard protocols. Results: AMS demonstrated increased aqueous solubility, crystallinity and slight increase in flow properties. There was a reduction in swelling and hydration capacities, amylose content as well as viscosity of the modified starch. Scanning electron microscopy analysis showed that the integrity of the modified starch granules were maintained and there was no disruption of the granular structure. Fourier transform infrared spectrophometer data confirmed the hydrolysis of NS with the increase in the intensity of the O-H stretch. AMS met United States Pharmacopoeia requirements in terms of microbiological quality, however, there was presence of Aspergillus niger. Conclusion: Modification of Borassus aethiopum shoot starch by acid treatment led to desirable improvement in some of its physicochemical properties which could improve its functional properties in pharmaceutical industries.en_US
dc.identifier.citationAzubuike C. P., Adeluola A. O., Mgboko M.S., Shadrack J. & Madu S. J. (2018). Physicochemical and microbiological evaluation of acid modified native starch derived from Borassus aethiopum (family Arecaceae) shoot. Tropical Journal of Pharmaceutical Research, 17 (5): 883-890.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7833
dc.language.isoenen_US
dc.publisherPharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeriaen_US
dc.relation.ispartofseriesTropical Journal of Pharmaceutical Research;Vol.17(5)
dc.subjectNative starchen_US
dc.subjectAcid-modified starchen_US
dc.subjectBorassus aethiopumen_US
dc.subjectMicrobiological qualityen_US
dc.subjectPhysicochemical propertiesen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titlePhysicochemical and microbiological evaluation of acid modified native starch derived from Borassus aethiopum (Arecaceae) shooten_US
dc.typeArticleen_US
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