Picard Iteration Method to Kinetic Analysis of Thermal Inactivation of Enzyme as Applied in Biotechnology

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dc.contributor.authorAdeleye, O.A
dc.contributor.authorSobamowo, M.G
dc.date.accessioned2019-08-20T09:52:35Z
dc.date.available2019-08-20T09:52:35Z
dc.date.issued2018
dc.descriptionStaff Publicationsen_US
dc.description.abstractIn this work, Picard iteration method is used to obtain analytical expressions for the prediction of molar concentration of native and denatured jack bean urease (EC 3.5.1.5) through the three-reaction steps kinetic model of thermal inactivation of the urease. The obtained solutions are used to study the kinetics of thermal inactivation of the enzyme as applied in biotechnology. The analytical solutions are verified with numerical solutions using Runge –Kutta with shooting method and good agreements are established between the solutions. From the parametric studies using the iterative method, the molar concentration of native enzyme decreases as the time increases while the molar concentration of the denatured enzyme increases as the time increases. The time taken to reach the maximum value of the molar concentration of native enzyme is the same as the time taken to reach the minimum value of the molar concentration of the denature enzyme. The information given in this theoretical investigation will assist in the kinetic analysis of the experimental results over handling rate constants and molar concentrationsen_US
dc.identifier.citationAdeleye, A. O., & Sobamowo, M. G. (2018). Picard Iteration Method to Kinetic Analysis of Thermal Inactivation of Enzyme as Applied in Biotechnology. International Journal of Advanced Design & Manufacturing Technology, Vol.11(4).en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/4595
dc.language.isoenen_US
dc.publisherInternational Journal of Advanced Design and Manufacturing Technologyen_US
dc.subjectEnzymeen_US
dc.subjectIteration Methoden_US
dc.subjectJack Bean Ureaseen_US
dc.subjectThermal Activationen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCESen_US
dc.titlePicard Iteration Method to Kinetic Analysis of Thermal Inactivation of Enzyme as Applied in Biotechnologyen_US
dc.typeArticleen_US
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