Case Report on Pleural Empyema Thoracis and Urinary Tract Infection Caused by Chromobacterium violaceum from Lagos, Nigeria
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Date
2019-02-07
Authors
Olalekan, A
Itua, F
Mutiu, B
Egwuatu, T
Akinloye, O
Iwalokun, B
Journal Title
Journal ISSN
Volume Title
Publisher
Hindawi Case Reports in Medicine
Abstract
Chromobacterium violaceum has been implicated as an important cause of invasive diseases such as septicaemia in neonates and
immune-compromised adults with high risk of misdiagnosis, mistreatment, and poor outcomes. Here, we report three new cases
of C. violaceum infections in three different hospitalised patients with empyema thoracis (one case) and urinary tract infections
(two cases) in a tertiary Hospital in Lagos, Nigeria, and the diagnosis was confirmed with the MALDI-TOF MS instrument. )e
patients were admitted and treated with parenteral antibiotics (ciprofloxacin, cefotaxime, and ceftriaxone) and discharged after
clinical cure. Clinical and Laboratory findings from this study revealed C. violaceum as an emerging and an “underdiagnosed”
pathogen causing human infections in Nigeria with ciprofloxacin identified as an effective empirical treatment. Follow-up of cases
treated with microbiologically efficacious antibiotics indicates a good treatment outcome.
Description
Keywords
Pleural Empyema Thoracis, Urinary Tract Infection, Chromobacterium violaceum, MALDI-TOF