The role of transrectal ultrasound-guided fine-needle aspiration biopsy in the diagnosis of prostate cancer: Sextant versus extended protocol

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dc.contributor.authorOliyide, A.
dc.contributor.authorTijani, K.
dc.contributor.authorJeje, E.
dc.contributor.authorAnunuobi, C.
dc.contributor.authorAdeyomoye, A.
dc.date.accessioned2019-11-08T14:10:07Z
dc.date.available2019-11-08T14:10:07Z
dc.date.issued2017-10
dc.descriptionStaff publicationsen_US
dc.description.abstractAim and Objectives: The aim of this study is to compare the prostate cancer detection rates of sextant and extended transrectal ultrasound (TRUS)‑guided fine‑needle aspiration biopsy (FNAB) protocols. Materials and Methods: This was a prospective study of 96 patients investigated for prostate cancer. An extended 10‑aspiration TRUS‑guided FNAB using a 22G Echotip Chiba needle was performed. Inclusion criteria included the presence of one or more of the following: Abnormal digital rectal examination (DRE) findings, persistently elevated prostate specific antigen, and abnormal prostatic imaging. A set of traditional sextant aspirations were carried out as well as four laterally guided aspirations taken from the middle base of the peripheral zone on either side. The cancer detection rates of sextant and extended (combination of sextant and lateral) FNAB protocols were determined and compared. The value of P < 0.05 was considered statistically significant. Results: The overall cancer detection rate was 24%. Benign cases were reported in 71.8% of patients and 4.2% reported as suspicious. Of the 23 patients’ aspirations positive for malignancy, 16 (69.6%) were detectable by the sextant protocol while the lateral protocol detected 21 (91.3%). Two cancers were detected by the sextant protocol only (where the lateral technique was negative for malignancy), 7 cancers were detected by the lateral protocol only while 14 cancers were positive in both the sextant and lateral protocols. The extended protocol showed a statistically significant 30.4% increase in cancer detection over the traditional sextant (P = 0.007). Conclusion: The extended protocol rather than the sextant protocol should be offered to patients who require FNAB of the prostate as the optimum FNAB protocol.en_US
dc.identifier.citationOliyide AE, Tijani KH, Jeje EA, Anunnobi CC, Adeyomoye AA, Ojewola RW, et al. The role of transrectal ultrasoundguided fine-needle aspiration biopsy in the diagnosis of prostate cancer: Sextant versus extended protocol. Niger Postgrad Med J 2017;24:236-9.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6776
dc.language.isoenen_US
dc.publisherWalters Kluwer/Medknowen_US
dc.subjectDetection rateen_US
dc.subjectExtendeden_US
dc.subjectFine-needle aspiration biopsyen_US
dc.subjectProstrate canceren_US
dc.subjectSextanten_US
dc.subjectResearch Subject Categories::MEDICINE::Surgeryen_US
dc.titleThe role of transrectal ultrasound-guided fine-needle aspiration biopsy in the diagnosis of prostate cancer: Sextant versus extended protocolen_US
dc.typeArticleen_US
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