Adverse drug reactions amongst adult patients admitted in Lagos State University Teaching Hospital Lagos, Nigeria

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dc.contributor.authorAderemi-Williams, R.I.
dc.contributor.authorAwodele, O.
dc.contributor.authorBoyle, C.A.
dc.date.accessioned2019-11-21T12:31:37Z
dc.date.available2019-11-21T12:31:37Z
dc.date.issued2015
dc.descriptionStaff Publicationsen_US
dc.description.abstractBACKGROUND: Adverse drug reaction (ADR) is a global drug therapy problem. It has been rated as one of the top leading causes of morbidity and mortality. In Nigeria, not much is known about ADRs especially with the existing weak post marketing surveillance for monitoring drug use, and its effect on the population. OBJECTIVES: The study is aimed at determining the incidence of ADRs, presentations of ADRs, classes of drugs that frequently cause ADRs and predictors of ADRs in adult medical in-patients in LASUTH. METHOD: A retrospective study of six hundred and twenty four (624) case notes of all patients admitted to the medical wards in LASUTH between January 1, 2009 and December 31, 2009 was carried out. Information obtained included age, gender, and adverse drug reaction and drug details. The results obtained were analyzed using SPSS version 16 statistical software. Level of significance was set at p ≤ 0.05. RESULTS: A total of 624 case notes consisting of 358 males and 266 females were assessed. The number of patients who experienced adverse drug reactions was 67 (n = 624, 10.7%). The incidence rate of ADRs in LASUTH from the study was 10.7 per 100 patients' population. Most of the ADRs observed were type A reactions (97.8%). Mostly implicated classes of drugs were antidiabetics (26.7%) and NSAIDs (29.3%). CONCLUSION: The incidence rate of ADRs was 10.7%. ADRs which are predictable and preventable occur in hospitalized patients, such may be prevented or minimized by implementing measures to target specific drugs that are commonly suspected.en_US
dc.identifier.citationAderemi-Williams, R.I., Awodele, O. and boyle, C.A. (2015). Adverse drug reactions amongst adult patients admitted in Lagos State University Teaching Hospital Lagos, Nigeria. Current Drug Safety, Vol.10(2).en_US
dc.identifier.otherDOI:10.2174/1574886309666140601211211
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6939
dc.language.isoenen_US
dc.publisherBentham Scienceen_US
dc.relation.ispartofseriesCurrent Drug Safety;Vol.10(2)
dc.subjectAdulten_US
dc.subjectAdverse drug reactionsen_US
dc.subjectHospitalisationen_US
dc.subjectMedical wardsen_US
dc.subjectPolypharmacyen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleAdverse drug reactions amongst adult patients admitted in Lagos State University Teaching Hospital Lagos, Nigeriaen_US
dc.typeArticleen_US
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