Assessment of predictors of treatment outcome among patient with bacteria odontogenic infection
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Despite the increasing availability of antimicrobial therapy and healthcare services, odontogenic orofacial infections remain a cause of admission and mortality of patients. Subjects who presented with bacterial odontogenic orofacial space infection and satisfied inclusion criteria were included. Incision and drainage/decompression was performed for all anatomic fascial spaces that were involved. All subjects received empirical antibiotics and MCS samples collected were cultured for aerobic and anaerobic organisms. There were 30 males and 25 females with a male-to-female ratio of 1.2:1. Of the 55 cases seen, majority (39) presented with abscess, 7 with Ludwig’s angina and 5 with necrotising fasciitis. Forty-two (76.4%) of specimen sent for MCS yielded positive culture for bacteria. Gram negative aerobes (25) were the most common bacteria and the least isolated were anaerobes (8). Overall, 52% of isolated organisms were sensitive to amoxicillin-clavulanate, 70% were sensitive to Ceftriaxone while 24% were resistant to both antibiotics. Subjects with clinical diagnosis of abscess or cellulitis were more likely to have a successful outcome without complications. The only significant predictors of outcome were haemoglobin level and number of spaces involved. Organisms involved in odontogenic infections were more sensitive to Ceftriaxone making it a better empirical antibiotic to Amoxicillin-clavulanate for severe odontogenic infections. Subjects with clinical diagnosis of abscess or cellulitis were more likely to have a successful outcome than those with necrotising fasciitis or Ludwig’s angina. Haemoglobin level and number of spaces involved were the only significant predictors of outcome. KEYWORDS: Bacterial, Odontogenic, Orofacial space, Infections, Sensitivity, Outcome
Bacteria , Odontogenic infections , Predictors , Outcome , Antibiotics , Research Subject Categories::ODONTOLOGY
Adamson OO, Gbotolorun OM, Odeniyi O, Oduyebo OO, Adeyemo WL. Assessment of predictors of treatment outcome among patient with bacteria odontogenic infection. 13th Annual Conference and Fair, University of Lagos. August 2018. (Poster presentation).