Atherogenic profile in diabetes mellitus - a Nigerian report

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Date
2009-10
Authors
Ogbera, A
Fasanmade, O
Chinenye, S
Akinlade, A
Journal Title
Journal ISSN
Volume Title
Publisher
International diabetes federation
Abstract
Aims: Diabetes mellitus (DM) is a disorder that is often associated with cardiovascular events and underlying lipid abnormalities. This report seeks to determine the atherogenic profile of DM. Methods: A total of 600 patients with DM aged between 22 – 79 years were evaluated for lipid abnormalities. The anthropometric indices, glycosylated haemoglobin, and pattern of DM treatment were noted. Total cholesterol (TCHOL), triglyceride (TG), high-density lipoproteins (HDL) and low-density lipoproteins (LDL) cholesterol were measured. Test statistics used included student’s t test and X2 . Results: The mean (SD) age and age range of the study subjects was 58 (10) years and 22-79 years respectively. The ratio of subjects with type 1 to 2 DM was 15:565. The prevalence of lipid abnormalities was 89%. The prevalence of elevated LDL-C reduced HDL, and elevated TG were 74%, 53%, and 13% respectively. The prevalence of elevated TCHOL/HDL ratio was 56% with a female preponderance. There were notable gender, type of DM and BMI impact on TCHOL and LDL, TG and HDL respectively. Conclusions: The prevalence of lipid abnormalities of Nigerian patients with DM is high and the pattern of abnormalities differ from what obtained elsewhere
Description
Scholarly articles
Keywords
Lipids , Diabetes , Anthropometric indices , Treatment , Research Subject Categories::MEDICINE
Citation
Ogbera A, Fasanmade O, Chinenye S, Akinlade A. Atherogenic profile in diabetes mellitus - a Nigerian report. Poster 1039, IDF Book of Abstracts, Montreal, Canada