Parkinson's disease in Africa: A systematic review of epidemiologic and genetic studies

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dc.contributor.authorOkubadejo, N.U.
dc.contributor.authorBower, J.H.
dc.contributor.authorRocca, W.A.
dc.contributor.authorMaraganore, D.M.
dc.date.accessioned2019-11-04T07:47:39Z
dc.date.available2019-11-04T07:47:39Z
dc.date.issued2006-12
dc.descriptionStaff publicationsen_US
dc.description.abstractParkinson's disease (PD) occurs worldwide, but little is known about PD in Africa. We systematically reviewed publications on PD in Africa, with emphasis on epidemiologic and genetic studies. Articles published between 1944 and December 2004 were identified using several strategies. The studies emanated from 13 African countries (Kenya, Uganda, Tanzania, Ethiopia, Nigeria, Senegal, Ghana, Togo, Libya, Tunisia, Algeria, Zimbabwe, and South Africa). The publications fell into four categories: clinical series (n = 17), prevalence studies (n = 7), incidence studies (n = 1), and genetic studies (n = 3). The clinical series documented the occurrence of PD in Africa and described its clinical characteristics. The prevalence studies suggested some intracontinental geographic variation in PD prevalence. Overall, the prevalence figures and the incidence rates of PD in Africa appeared lower than those reported for European and North American populations. Few genetic studies of PD have been reported from Africa, and none in blacks. There are no case-control or cohort studies of PD reported from Africa. This review provides a summary of PD research in Africa over the past 60 years and highlights the information gaps and potential areas for future research.en_US
dc.identifier.citationOkubadejo NU, Bower JH, Rocca WA, Maraganore DM. Parkinson's disease in Africa: A systematic review of epidemiologic and genetic studies. Mov Disord. 2006 Dec;21(12):2150-6.en_US
dc.identifier.otherPubMed PMID: 17044056
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6707
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectParkinson diseaseen_US
dc.subjectAfricaen_US
dc.subjectGeneticsen_US
dc.subjectEpidemiologyen_US
dc.subjectPrevalenceen_US
dc.subjectIncidenceen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleParkinson's disease in Africa: A systematic review of epidemiologic and genetic studiesen_US
dc.typeArticleen_US
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