Evaluation of maternal serum levels of dehydroepiandrosterone sulphate and its association with successful labour outcome among parturients undergoing spontaneous labour at term

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dc.contributor.authorOkunowo, A.A
dc.contributor.authorAjayi, G.O
dc.contributor.authorAdegbola, O.
dc.date.accessioned2020-02-21T10:50:49Z
dc.date.available2020-02-21T10:50:49Z
dc.date.issued2017
dc.descriptionStaff publicationsen_US
dc.description.abstractThis study evaluated maternal serum levels of dehydroepiandrosterone sulphate (DHEAS) in spontaneous labour and its association with successful labour at term. A cross-sectional observational study was carried out on 140 parturients. Their blood samples were collected in active labour; allowed to clot, centrifuged, separated and stored at -20 °C before analysis for DHEAS was done using the ELISA method. Labour was termed successful when vaginal delivery was achieved. Serum DHEAS levels were higher among parturients with successful labour compared to women with unsuccessful outcome (p = 0.001). DHEAS level was also higher among parturients who did not require oxytocin augmentation compared with those who required it (p = .001). The odds ratio and incidence of successful labour increased significantly as DHEAS level increased above a critical value of 1.5 μg/ml (p = .001). The association between serum DHEAS level and successful labour remained significant after adjusting for other variables (p = .002).en_US
dc.identifier.citationOkunowo, A.A., Adegbola, O. and Ajayi, G.O. (2017). Evaluation of maternal serum levels of dehydroepiandrosterone sulphate and its association with successful labour outcome among parturients undergoing spontaneous labour at term. Journal of Obstetrics and Gynaecology, 37(2):191-194.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7772
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.ispartofseriesJournal of Obstetrics and Gynaecology;Vol.37(2)
dc.subjectDehydroepiandrosterone sulphateen_US
dc.subjectSpontaneous labouren_US
dc.subjectLabour outcomeen_US
dc.subjectParturientsen_US
dc.subjectPregnant Womenen_US
dc.subjectResearch Subject Categories::MEDICINE::Surgeryen_US
dc.titleEvaluation of maternal serum levels of dehydroepiandrosterone sulphate and its association with successful labour outcome among parturients undergoing spontaneous labour at termen_US
dc.typeArticleen_US
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