Antimicrobial and antioxidant properties of African medicinal plants

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dc.contributor.authorBello, M. D.
dc.contributor.authorAderolu, A.Z.
dc.contributor.authorLawal, M.O.
dc.contributor.authorSoyinka, O.O.
dc.contributor.authorAdeleke, T.A.
dc.date.accessioned2019-11-19T09:23:33Z
dc.date.available2019-11-19T09:23:33Z
dc.date.issued2017
dc.descriptionStaff publicationsen_US
dc.description.abstractObjective: To study antioxidant and antimicrobial properties of Terminalia catappa, Psidium guajava, Alstonia boonei, Morinda lucida (M. lucida) and Spondias mombin leave extracts using ethanol, petroleum-ether and aqueous media. Methods: The free radical 2, 2-diphenyl-1-picrylhydroazyl was used to measure scavenging activities of extracts, while phenolic and flavonoid content were estimated by spectrophotometry. Antibacterial screening of extracts was done by determining zone of inhibition using disc diffusion method. Plant extracts were tested against five strains of Gram-positive and Gram-negative bacteria. After sterilization, the discs were loaded with concentrations of broad spectrum ciprofloxacin, and prepared extract solutions of different concentrations were refrigerated for 24 h. Determination of minimum inhibitory concentration of extracts in the screening assay was according to micro-broth dilution, while determination of minimum bactericidal concentration was carried out by agar diffusion. Results: The highest radical scavenging effect was found in petroleum ether extracts of all the plants with M. lucida and Psidium guajava having the highest and lowest values respectively. Aqueous solvent recorded highest phenolic content in all extracts with the exception of M. lucida. Flavonoid content was extracted better from Alstonia boonei and M. lucida with ethanol, while aqueous solvent extracted more from the other plants. With exception of extracts from petroleum ether, all others exhibited varying levels of antibacterial activities against E. coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholera and Staphylococcus aureus. Conclusions: This study proved that all crude extracts showed strong antioxidant and antimicrobial potentials, which qualified them as nutraceuticals in fish feed production.en_US
dc.identifier.citationAderolu, A.Z., Lawal, M.O., Soyinka, O.O., Adeleke, A.T., Bello, M.D. (2017). Antimicrobial and antioxidant properties of African medicinal plants. Journal of Coastal Life Medicine, 5(1): 16-21.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6916
dc.language.isoenen_US
dc.publisherJournal of Coastal Life Medicineen_US
dc.relation.ispartofseriesJournal of Coastal Life Medicine;Vol.5(1)
dc.subjectTotal flavonoid contenten_US
dc.subjectTotal phenolic contenten_US
dc.subjectAntioxidant activityen_US
dc.subjectAntimicrobial activityen_US
dc.subjectAfrican medicinal plantsen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCESen_US
dc.titleAntimicrobial and antioxidant properties of African medicinal plantsen_US
dc.typeArticleen_US
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