How does Octyl –2- cyanoacrylate tissue adhesive compare with prolene sutures in cleft lip repair?
| dc.contributor.author | James, O. | |
| dc.contributor.author | Adekunle, A.A. | |
| dc.contributor.author | Adeyemo, W.L. | |
| dc.date.accessioned | 2021-02-01T09:54:51Z | |
| dc.date.available | 2021-02-01T09:54:51Z | |
| dc.date.issued | 2021-01-29 | |
| dc.description | Scholarly articles | en_US |
| dc.description.abstract | Purpose Comparative evidence of the usefulness of octyl-2-cyanoacrylate tissue adhesive in cleft lip epidermal skin closure especially in Africans is still lacking. This study aimed to compare the outcome of wound healing following the use of Dermabond® tissue adhesive and 5/0 Prolene® sutures in cleft lip repair. Methods This was a prospective randomized controlled clinical study. Sampled population were patients undergoing cleft lip repair at a tertiary health facility in Lagos, Nigeria. Study subjects were randomly allocated to either Group A (Dermabond) or Group B (suture). The predictor variable was the type of material used in skin closure; primary outcome variable was the esthetics of the resulting scar and secondary outcome variables were wound healing complications. Assessment of the 3 months post-operative wound scar was done using the Cosmetic Visual Analogue scale (CVAS) and the Hollander Wound Evaluation scale (HWES). Calculated sample size was 14 participants per group. Descriptive and comparative statistics were computed and the P value was set at <0.05. Results Analysis of result included 38 participants. Median age was 4 months and 52.6% were females. Two cases (5.3%) of wound healing complications were recorded (1 in each group). Blinded evaluation of the 3 months post-operative photographs yielded a mean CVAS score of 86.0 (± 11.2) and HWES score of 5.0 (± 0.9) for group A and a mean CVAS score of 76.5 (± 14.5) and HWES score of 4.5 (± 1.1) for group B. There was no statistically significant difference between these 2 groups based on the CVAS ( p = .052) and HWES ( p = .152). Conclusion The results of this study suggest Dermabond® offers a comparable cosmetic outcome as 5/0 Prolene® suture in epidermal closure of cleft lip. There was no statistically significant difference in wound complications and wound cosmetic scores between the 2 groups. | en_US |
| dc.description.sponsorship | Central Research Committee (CRC) University of Lagos | en_US |
| dc.identifier.citation | James O, Adekunle AA, Adeyemo WL. How does Octyl –2- cyanoacrylate tissue adhesive compare with prolene sutures in cleft lip repair? J Oral Maxillofac Surg 2021. DOI:https://doi.org/10.1016/j.joms.2021.01.026 | en_US |
| dc.identifier.other | https://doi.org/10.1016/j.joms.2021.01.026 | |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/9131 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.subject | Cyanoacrylate tissue adhesive | en_US |
| dc.subject | Prolene | en_US |
| dc.subject | Cleft lip | en_US |
| dc.subject | Repair | en_US |
| dc.subject | Research Subject Categories::ODONTOLOGY | en_US |
| dc.title | How does Octyl –2- cyanoacrylate tissue adhesive compare with prolene sutures in cleft lip repair? | en_US |
| dc.type | Article | en_US |