Prognostic factors in the management outcome of carcinoma of the larynx in Lagos.

Simple item page
dc.contributor.authorSomefun, OA
dc.contributor.authorNwawolo, CC
dc.contributor.authorOkeowo, PA
dc.contributor.authorAlabi, SB
dc.contributor.authorAbdul-Kareem, FB
dc.contributor.authorBanjo, AA
dc.contributor.authorElesha, SO
dc.date.accessioned2020-07-16T16:20:10Z
dc.date.available2020-07-16T16:20:10Z
dc.date.issued2003
dc.description.abstractThis is a retrospective analysis on the prognostic factors in the management outcome of clinically and histologically diagnosed carcinoma of larynx seen in Lagos University Teaching Hospital between 1996-1999. Various prognostic factors have been documented as determinants on the probable outcome of carcinoma of the larynx, such as duration of symptoms, smoking, medical status of the patient, degree of differentiation, size and site of tumour and presence of cervical lymph node. Thirty-six patients between 1996-1999 were reviewed, with a male to female ratio of 11:1, and peak age group of occurrence in 50-59 years, majority (86.12%) of which were non-smokers who presented in varied degrees of airway obstruction necessitating pre-treatment tracheostomy in 70% of the patients with more than 50% presenting within 3-6 months of onset of initial symptom. The tumours were staged clinically and histology revealed well differentiated T3 glottic tumour without any clinically palpable neck node in more than 50% of the patients which should predict a better outcome. But the interplay of many prognostic variables like pre-treatment tracheostomy and its attendant complications, supposed biological aggressive tumour in a non-smoker, coupled with treatment biased by patients, high costs of treatment, logistics and poor follow up compliance, resulted in poor outcome of our management.en_US
dc.identifier.citationThe Nigerian Postgraduate Medical Journal, 01 Jun 2003, 10(2):103-106en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/8628
dc.language.isoenen_US
dc.publisherNigerian Postgraduate Medical Journalen_US
dc.titlePrognostic factors in the management outcome of carcinoma of the larynx in Lagos.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Prognostic factors in the management outcome of carcinoma of the larynx in Lagos..png
Size:
77.66 KB
Format:
Portable Network Graphics
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Anatomic and Molecular Pathology- Scholarly Publications