The effect of starch and surfactants on the granulation of soluble and insoluble powders
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Date
1983-06
Authors
Obagaiye, M.O
Jaiyeoba, K.T.
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Publisher
3rd Congress International Conference on Pharmaceutical Technology
Abstract
Powders of lactose and calcium carbonate have been granulated by the massing and screening method. The effects of including starch or both starch and surfactants in the granule formula have been studied with respect to size and friability of the final granules. The addition of 10 % starch to either lactose or calcium carbonate reduced the mean granule size and increased granule friability. The effect of starch on granule size was compensated for, by the presence of sodium lauryl sulphate, particularly in the granules containing lactose
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Obagaiye and Jaiyeoba 1983.The effect of starch and surfactants on the granulation of soluble and insoluble powders