Outcomes of COVID-19 patients with comorbidities in southwest Nigeria

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dc.contributor.authorOsibogun, A
dc.contributor.authorBalogun, M
dc.contributor.authorAbayomi, A
dc.contributor.authorIdris, J
dc.contributor.authorKuyini, Y
dc.contributor.authorOdukoya, O
dc.contributor.authoret al
dc.date.accessioned2022-09-19T09:29:54Z
dc.date.available2022-09-19T09:29:54Z
dc.date.issued2021
dc.descriptionScholarly articleen_US
dc.description.abstractBackground Data on the comorbidities that result in negative outcomes for people with COVID-19 are currently scarce for African populations. This study identifies comorbidities that predict death among a large sample of COVID-19 patients from Nigeria. Methods This was a retrospective analysis of medical records for 2184 laboratory confirmed cases of COVID-19 in Lagos, southwest Nigeria. Extracted data included age, sex, severity of condition at presentation and self-reported comorbidities. The outcomes of interest were death or discharge from facility. Results Most of the cases were male (65.8%) and the median age was 43 years (IQR: 33–55). Four hundred and ninety-two patients (22.5%) had at least one comorbidity and the most common amongst them were hypertension (74.2%) and diabetes (30.3%). The mortality rate was 3.3% and a significantly higher proportion of patients with comorbidities died compared to those with none. The comorbidities that predicted death were hypertension (OR: 2.21, 95%CI: 1.22–4.01), diabetes (OR: 3.69, 95% CI: 1.99–6.85), renal disease (OR: 12.53, 95%CI: 1.97–79.56), cancer (OR: 14.12, 95% CI: 2.03–98.19) and HIV (OR: 1.77–84.15]. Conclusion Comorbidities are prevalent and the associated risk of death is high among COVID-19 patients in Lagos, Nigeria. Public enlightenment, early identification and targeted care for COVID-19 cases with comorbidities are recommended as the pandemic evolves.en_US
dc.description.sponsorshipGovernment of Lagos Stateen_US
dc.identifier.citationOsibogun A, Balogun M, Abayomi A, Idris J, Kuyinu Y, Odukoya O, et al. Outcomes of COVID-19 patients with comorbidities in southwest Nigeria. PLOS ONE. 2021; 16(3): e0248281. https://doi.org/10.1371/journal.pone.0248281en_US
dc.identifier.other. https://doi.org/10.1371/journal.pone.0248281
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/11518
dc.language.isoenen_US
dc.subjectCOVID-19en_US
dc.subjectComorbiditiesen_US
dc.subjectCoronavirusen_US
dc.subjectSARS-CoV-2 virusen_US
dc.subjectPandemicen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleOutcomes of COVID-19 patients with comorbidities in southwest Nigeriaen_US
dc.typeArticleen_US
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