Breast Cancer in a Lagos Facility-Implications for the Institution of a Cancer Screening Programme

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dc.contributor.authorIkeri, NZ
dc.contributor.authorOguntunde, OA
dc.contributor.authorIgbokwe, U
dc.contributor.authorAbdulkareem, FB
dc.contributor.authorBanjo, AAF
dc.date.accessioned2020-05-01T13:48:00Z
dc.date.available2020-05-01T13:48:00Z
dc.date.issued2018
dc.descriptionOriginal researchen_US
dc.description.abstractObjective: There are significant epidemiological and biological differences between breast cancer in blacks and whites which have wide-reaching implications for the institution of an effective cancer screening programme in Nigeria. The aim of this study was to describe the clinicopathologic features of breast cancer diagnosed in our facility and to discuss their implications for cancer screening. Methods: A retrospective review of the forms, slides, and results of breast cancer cases received in our facility over an 8-year period was carried out, as well as a systematic review of the characteristics of breast cancer in Nigeria, Africa, the US, and the UK. Result: A total of 832 cancers were seen with a mean age of 49 years. Most cases (97%) were invasive ductal carcinomas not otherwise specified, high grade (41.9%), and unassociated with ductal carcinoma in situ (52.3%). Triple-negative tumors were the commonest immunohistochemical type seen (42.1%), and these were less likely to have an intraductal component (p = 0.0048). Luminal-type tumours were more likely to be low grade (p = 0.0005). The majority of cases presented in advanced stages with no statistically significant difference among the different immunohistochemical subtypes (p = 0.7949). Conclusion: The significant epidemiological and biological differences between breast cancer in Lagos and in western populations are important for the establishment of an effective breast cancer screening programme uniquely tailored for the Nigerian populationen_US
dc.description.sponsorshipNilen_US
dc.identifier.citationIkeri NZ, Oguntunde OA, Igbokwe U, Abdulkareem FB, Banjo AA. Pathobiology. 2018;85(4):254-260.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/8257
dc.language.isoenen_US
dc.publisherPathobiologyen_US
dc.subjectBreast; Cancer; Lagos; Screening.en_US
dc.titleBreast Cancer in a Lagos Facility-Implications for the Institution of a Cancer Screening Programmeen_US
dc.typeArticleen_US
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