SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF OXOVANADIUM(IV) COMPLEXES OF SCHIFF BASES DERIVED FROM SUBSTITUTED SALICYLALDEHYDE AND DIAMINES
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Date
2011-08
Authors
Nejo, A.A.
Nejo, A.O.
Kolawole, G.A.
Muller, C.J.
Journal Title
Journal ISSN
Volume Title
Publisher
INTERNATIONAL JOURNAL OF DRUG FORMULATION AND RESEARCH
Abstract
A series of oxovanadium(IV) complexes involving symmeticaltetradentate Schiff bases derived from substituted
salicylaldehyde and diamine have been prepared and characterized byelemental analyses, 1H NMR, infrared,
electron paramagnetic resonance, electronic spectral, cyclic voltammetry and room temperature magnetic
susceptibility measurements. The purity of the ligands and metal complexes are confirmed by microanalysis
Infrared spectra reveals strong V=O bands in the range 967-982 cm–1, which confirms that the complexes are
essentially monomeric with square pyramidal coordination geometry. The room temperature magnetic moments
of 1.77-1.80 BM for the complexes confirmed that the complexes are V(IV) complexes, with d1 configuration.
The Schiff bases and their complexes were screened for in vitro antibacterial activities against ten human
pathogenic bacteria. The antibacterial results showed that the majority of the Schiff bases were more active than
their respective metal complexes.
A series of oxovanadium(IV) complexes involving symmeticaltetradentate Schiff bases derived from substituted salicylaldehyde and diamine have been prepared and characterized byelemental analyses, 1H NMR, infrared, electron paramagnetic resonance, electronic spectral, cyclic voltammetry and room temperature magnetic susceptibility measurements. The purity of the ligands and metal complexes are confirmed by microanalysis Infrared spectra reveals strong V=O bands in the range 967-982 cm–1, which confirms that the complexes are essentially monomeric with square pyramidal coordination geometry. The room temperature magnetic moments of 1.77-1.80 BM for the complexes confirmed that the complexes are V(IV) complexes, with d1 configuration. The Schiff bases and their complexes were screened for in vitro antibacterial activities against ten human pathogenic bacteria. The antibacterial results showed that the majority of the Schiff bases were more active than their respective metal complexes.
A series of oxovanadium(IV) complexes involving symmeticaltetradentate Schiff bases derived from substituted salicylaldehyde and diamine have been prepared and characterized byelemental analyses, 1H NMR, infrared, electron paramagnetic resonance, electronic spectral, cyclic voltammetry and room temperature magnetic susceptibility measurements. The purity of the ligands and metal complexes are confirmed by microanalysis Infrared spectra reveals strong V=O bands in the range 967-982 cm–1, which confirms that the complexes are essentially monomeric with square pyramidal coordination geometry. The room temperature magnetic moments of 1.77-1.80 BM for the complexes confirmed that the complexes are V(IV) complexes, with d1 configuration. The Schiff bases and their complexes were screened for in vitro antibacterial activities against ten human pathogenic bacteria. The antibacterial results showed that the majority of the Schiff bases were more active than their respective metal complexes.
Description
Keywords
Oxovanadium(IV), Schiff bases, Antibacterial activity , Oxovanadium(IV), Schiff bases, Antibacterial activity