SYNTHESIS, CHARACTERIZATION AND STRUCTURE ACTIVITY RELATIONSHIP OF SCHIFF BASES DERIVED FROM 2-AMINOPHENOL AND SUBSTITUTED BENZALDEHYDES
| dc.contributor.author | Fasina, T.M. | |
| dc.contributor.author | Ejiah, F.N. | |
| dc.contributor.author | Oloba-whenu, O.A. | |
| dc.contributor.author | Revaprasadu, N. | |
| dc.contributor.author | Familoni, O.B. | |
| dc.date.accessioned | 2019-09-05T16:19:05Z | |
| dc.date.available | 2019-09-05T16:19:05Z | |
| dc.date.issued | 2017-02-23 | |
| dc.description.abstract | The structure-antibacterial activity of six Schiff bases synthesized from 2-aminophenol and substituted benzaldehydes was studied by relating the effect of substituent groups on antibacterial activity. The study showed that compounds with electron donating methoxy substituent exhibited higher inhibitory activity against the tested microorganisms than compounds bearing an electron withdrawing chloroor nitro substituent. Quantum chemical studies carried out on the compounds using density functional theory calculations (DFT) revealed that the activity of the Schiff bases is related to the electrostatic potential, ionization potential and alignment of the dipole moment with respect to the imine bond | en_US |
| dc.description.sponsorship | Tetfund | en_US |
| dc.identifier.citation | Fasina, T. M., Ejiah, F., Oloba-Whenu, O. A., Revaprasadu, N., & Familoni, O. B.(2017), SYNTHESIS, CHARACTERIZATION AND STRUCTURE ACTIVITY RELATIONSHIP OF SCHIFF BASES DERIVED FROM 2-AMINOPHENOL AND SUBSTITUTED BENZALDEHYDES,FUW trends in science & technology Journal, 2(1)252-256 | en_US |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/5302 | |
| dc.language.iso | en | en_US |
| dc.subject | Research Subject Categories::NATURAL SCIENCES::Chemistry::Inorganic chemistry | en_US |
| dc.subject | 2-aminophenol, antibacterial activity, schiff bases, quantum chemical studies | en_US |
| dc.title | SYNTHESIS, CHARACTERIZATION AND STRUCTURE ACTIVITY RELATIONSHIP OF SCHIFF BASES DERIVED FROM 2-AMINOPHENOL AND SUBSTITUTED BENZALDEHYDES | en_US |
| dc.type | Article | en_US |