Plasma total and ultrafiltrable calcium in normal pregnancy, hypertension in pregnancy and pre-eclampsia
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Date
2007-09
Authors
Oladipo, O.O.
Afolabi, B.B.
Okorodudu, A.O.
Journal Title
Journal ISSN
Volume Title
Publisher
Niger Postgrad Med J
Abstract
To measure the ultrafiltrable and total plasma calcium in normal pregnancy and pregnancies complicated with hypertension and pre-eclampsia. Total and ultrafiltrable calcium concentrations were measured in maternal plasma from non-pregnant (35), normal pregnant (35), Pregnancy induced hypertension (35) and pre-eclamptic (20) women. Plasma total calcium level was measured by the o'cresolphthalein method. Ultrafiltrate of plasma was obtained using the Amicon MPS-1 micro-partition device. There was no significant difference in the plasma total calcium level between the non- pregnant group and the pregnant group (normal, hypertensive and pre-eclamptic). However there was a significant reduction in the ultrafiltrable (protein free and complexed) calcium level in the pregnant group compared to the non-pregnant group (1.15mmol/L +/- 0.23 Vs 1.25mmol/L +/- 0.13) p<0.05. Measurement of the ultrafiltrable calcium in addition to total calcium assay may be more useful in assessing calcium status in normal and complicated pregnancies.
Description
Staff Publications
Keywords
Calcium , Pre-eclampsia , Ultra-filtrate , Micro-partition device , Research Subject Categories::MEDICINE::Surgery::Obstetrics and women's diseases
Citation
Oladipo OO, Afolabi BB, Okorodudu AO. Plasma total and ultrafiltrable calcium in normal pregnancy, hypertension in pregnancy and pre-eclampsia. Niger Postgrad Med J. 2007 Sep;14(3):213-6. PubMed PMID: 17767205.