Prospective case-control study of interictal depression and suicidal ideation in Nigerians with epilepsy.

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dc.contributor.authorOkubadejo, N.U.
dc.contributor.authorDanesi, M.A.
dc.contributor.authorAina, O.F.
dc.contributor.authorOjini, F.I.
dc.contributor.authorAdeyemi, J.D.
dc.contributor.authorOlorunshola, D.A.
dc.date.accessioned2019-11-02T14:35:38Z
dc.date.available2019-11-02T14:35:38Z
dc.date.issued2007-09
dc.description.abstractBACKGROUND: Co-morbid depression and suicidal ideation in people with epilepsy (PWE) in developing countries are under-recognised, and so may be consequently undertreated. This study was designed to determine the frequency and clinical correlates of interictal depression and suicidal ideation in PWE. PATIENTS AND METHODS: Using a prospective design, we evaluated 96 PWE and two groups of controls (103 age- and sex-matched population controls and 13 persons with DSM - IV diagnosis of major depression (controls with depression - CWD) without epilepsy. Depression was assessed using Zung Self-rating depression scale (scores =40 indicating depression). RESULTS: Depression was more prevalent in PWE (25/96 i.e. 26.0%) than normal controls (10/103 i.e. 9.7%) (P = 0.004). Suicidal ideation scores were similar for depressed PWE and depressed normal controls (1.7 +/-1.0 v. 1.5 +/- 1.0; P>0.05), but significantly higher in CWD (2.61.3; P=0.04). Among PWE, mean duration of epilepsy (years) was the only variable significantly related to depression (i.e. 12.7 8.8 in depressed PWE v. 8.3 6.6 in non-depressed PWE (P=0.01). CONCLUSION: Depressive symptomatology is a frequent co-morbidity in our tertiary care population of PWE. However, suicidal ideation is less common in contrast to persons with major depression.en_US
dc.identifier.citationOkubadejo NU, Danesi MA, Aina OF, Ojini FI, Adeyemi JD, Olorunshola DA. Prospective case-control study of interictal depression and suicidal ideation in Nigerians with epilepsy. Niger Postgrad Med J. 2007 Sep;14(3):204-8.en_US
dc.identifier.otherPubMed PMID: 17767203
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6672
dc.language.isoenen_US
dc.publisherNational Postgraduate Medical College of Nigeriaen_US
dc.subjectEpilepsyen_US
dc.subjectDepressionen_US
dc.subjectSuicidal ideationen_US
dc.subjectPsychopathologyen_US
dc.titleProspective case-control study of interictal depression and suicidal ideation in Nigerians with epilepsy.en_US
dc.typeArticleen_US
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