Evaluation of Baylis–Hillman Routes to 3- (Aminomethyl)coumarin Derivatives
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Date
2014
Authors
Olasupo, I
Rose, N.R.
Klein, R.
Adams, L.A.
Familoni, O.B.
Kaye, P. T.
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor & Francis Group, LLC
Abstract
The relative merits of two different Baylis–Hillman approaches toward the preparation of coumarin derivatives, containing peptide-like side chains, have been explored. In one approach, use of methyl acrylate as the activated alkene requires a protecting group strategy, an approach that is not necessary when using tert-butyl acrylate.
Description
Keywords
3-(Aminomethyl)coumarins; aza-Michael; Baylis–Hillman
Citation
DOI: 10.1080/00397911.2013.803575