Case report: Neonatal pancreatitis, chromosomal abnormality andduodenal stenosis in a newborn. A new syndrome?

dc.contributor.authorLadipo-Ajayi, O
dc.contributor.authorIhediwa, G
dc.contributor.authorAkinjo, AO
dc.contributor.authorAwolola, NO
dc.contributor.authorElebute, OA
dc.contributor.authorAdemuyiwa, AO
dc.date.accessioned2022-08-29T11:22:56Z
dc.date.available2022-08-29T11:22:56Z
dc.date.issued2020
dc.descriptionScholarly articleen_US
dc.description.abstractIntroduction: Pancreatitis is a dire clinical diagnosis with variable presentation in the paediatric population. Moreover, neonatal pancreatitis has been rarely reported in the English literature. Presentation of case: A newborn, product of a poorly supervised, pre-term gestation with pre-natally diagnosed intestinal obstruction, and post-natal clinical features of jaundice, vomiting, abdominal distension, aphonation and suspected chromosomal abnormalities. There was maternal hepatitis which was untreated. Diagnosed as duodenal atresia, the baby was investigated, resuscitated and had surgery. Intra-operative findings were of an omental bubble, duodenal stenosis with annular pancreas, coagulative necrosis of the pancreas and multiple intra peritoneal cheesy deposits. Following an unfortunate demise, autopsy confirmed pancreatitis and multiple congenital abnormalities. Discussion: Paediatric caregivers should be aware of the possibility of neonatal pancreatitis in jaundiced newborns with intestinal obstruction especially with a background of maternal viraemia. Conclusion: A constellation of unusual presentations as highlighted could be a pointer to an emerging syndrome. All paediatric caregivers should entertain a high index of suspicion of pancreatitis in such a case, investigate and expedite appropriate interventions to prevent mortality.en_US
dc.identifier.citationLadipo-Ajayi O, Ihediwa G, Akinjo AO, Awolola NA, Elebute OA, Ademuyiwa AE. Case report: Neonatal pancreatitis, chromosomal abnormality and duodenal stenosis in a newborn. A new syndrome? Int J Surg Case Rep. 2020;77:686-691. doi: 10.1016/j.ijscr.2020.11.114. Epub 2020 Nov 24. PMID: 33395874; PMCID: PMC7711185.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/11100
dc.language.isoenen_US
dc.publisherElsevier Ltden_US
dc.subjectAnnular pancreasen_US
dc.subjectNeonatal pancreatitisen_US
dc.subjectMaternal hepatitis infectionen_US
dc.subjectChromosomal defecten_US
dc.subjectCase reporten_US
dc.subjectResearch Subject Categories::MEDICINE::Surgeryen_US
dc.titleCase report: Neonatal pancreatitis, chromosomal abnormality andduodenal stenosis in a newborn. A new syndrome?en_US
dc.typeArticleen_US
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