A Nationwide Survey of Parkinson's Disease Medicines Availability and Affordability in Nigeria

Simple item page
dc.contributor.authorOkubadejo, N.U.
dc.contributor.authorOjo, O.O.
dc.contributor.authorWahab, K.W.
dc.contributor.authorAbubakar, S.A.
dc.contributor.authorObiabo, O.Y.
dc.contributor.authorSalawu, F.K.
dc.contributor.authorNwazor, E.O.
dc.contributor.authorAgabi, O.P.
dc.contributor.authorOshinaike, O.O.
dc.date.accessioned2019-10-31T08:07:18Z
dc.date.available2019-10-31T08:07:18Z
dc.date.issued2018-11-16
dc.descriptionStaff publicationsen_US
dc.description.abstractBackground and Objectives: Limited access to medicines can impact negatively on outcomes in people with Parkinson's disease (PD). The study objectives were to determine the availability and assess the affordability of antiparkinsonian medications in pharmacies across Nigeria. Methods: This was a cross-sectional nationwide study utilizing the World Health Organization/Health Action Initiative methodology. Strategically selected private- and public-sector pharmacies in the six geopolitical zones of Nigeria were surveyed for availability of medicines for management of early and advanced PD. The nine categories were: levodopa/peripheral decarboxylase inhibitors, dopamine receptor agonists, monoamine oxidase type B inhibitors, anticholinergics, catechol-o-methyl transferase inhibitors, atypical antipsychotics, antidepressants, antidementia drugs, and miscellaneous (e.g., drugs for orthostatism, urinary incontinence, and sleep disturbance). Unaffordability was defined as paying more than 1 days' wages (>N600 or > US$1.67) for a standard 30-day supply. Results: One hundred twenty-three pharmacies were surveyed (62 private [50.4%] and 61 public sector [49.6%]; range of 15-25 pharmacies in each geopolitical zone). Private exceeded public-sector availability across all nine categories of PD medicines (P < 0.05). The most available medicines were dopamine receptor agonists (68.3%; predominantly ergot-derived bromocriptine), anticholinergics (56.1%; mainly trihexyphenidyl), and l-dopa formulations (48%; mainly 250/25 l-dopa/carbidopa). Only two medications (trihexyphenidyl tablets and biperiden injection) were affordable. The average number of day's minimum wages for a 30-day supply of PD medicines was 41.3 days (range, 1-371). Conclusions: PD medicines access is limited in Nigeria. Strategies, including engagement of stakeholders to consider interventions to improve and prioritize PD medicines access, are urgently warranted.en_US
dc.description.sponsorshipInternational Parkinson and Movement Disorders Societyen_US
dc.identifier.citationOkubadejo NU, Ojo OO, Wahab KW, Abubakar SA, Obiabo OY, Salawu FK, Nwazor EO, Agabi OP, Oshinaike OO. A Nationwide Survey of Parkinson's Disease Medicines Availability and Affordability in Nigeria. Mov Disord Clin Pract. 2018 Nov 16;6(1):27-33en_US
dc.identifier.otherdoi: 10.1002/mdc3.12682
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6616
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofseriesMov Disord Clin Pract;Vol.6(1)
dc.subjectParkinson diseaseen_US
dc.subjectAfricaen_US
dc.subjectTreatmenten_US
dc.subjectLevodopaen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleA Nationwide Survey of Parkinson's Disease Medicines Availability and Affordability in Nigeriaen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Okubadejo NU et al. Nationwide Survey PD Medicine MDCP 2018.pdf
Size:
155.29 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medicine- Scholarly Publications