The Baylis–Hillman approach to quinoline derivatives
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Date
2006-09-25
Authors
Familoni, O.B.
Klaas, P.J.
Lobb, K.A.
Pakade, V.E.
Kaye, P.T.
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
Baylis–Hillman reactions of 2-nitrobenzaldehydes with various activated alkenes afford adducts that undergo reductive cyclisation to quinoline derivatives. The chemo- and regioselectivity of cyclisation appears to be influenced by the choice of both the substrate and the reagent system, and competing reactions have been observed.
Description
Staff Publication
Keywords
Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry::Organic synthesis , chemoselectivity , Regioselectivity , Baylis-Hillman reactions
Citation
Familoni, O. B., [Et...al] (2006). The Baylis–Hillman approach to quinoline derivatives. Organic & biomolecular chemistry, Vol.4(21), 3960-3965.