A Retrospective study on the treatment of adult tuberculosis in Lagos University Teaching Hospital
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Date
2011-10
Authors
Aderemi-Williams, R.I.
Ajamu, I.J.
Journal Title
Journal ISSN
Volume Title
Publisher
University of Lagos Press and Bookshop Ltd
Abstract
After decades of decline,Tuberculosis (TB) is increasing worldwide. The increase in TB casesand deaths has been linked to HIV co-infection. Nigeria is rankedfourth amongst the 22 countries that account for 80 per centof all the cases of TB recorded worldwide. The objectives of this study were to assess the treatmentof adult tuberculosis in Lagos University TeachingHospital(LUTH)and the outcomes of treatment. A retrospective case study of 64 adult TB patients attended to between January 2006-December, 2010 in LUTHwas done. Analysis of records showed thatTB was not confirmed in 6(9.6%) of the cases.Most (64.1%) patients were male, withTB occurringmore (69.9%) amongst patientswithin 20-40 years age range.Forty-four (69.8%) were employed and 40(62.5%) married. Diagnoses were mainly done with chest X-rays (90.6%),Acid Fast Bacilli tests (82.8%) and Erythrocyte Sedimentation Rates (82.8%). All (90.6%) of the patients were treated with Rifampicin, Isoniazid, Pyrazinamide and Ethambutol (R.1.P.E)combination throughout the period of treatment. Treatment outcomes showed high level (62.5%) of defaulters with only 15 (23.4%)of the patients cured. The study has revealed weakmonitoring of TB patients which has resulted to high number of default.ers. There is need for further research to investigatethe reasons for this and thereby prevent the danger of patients developing and transmitting multidrug resistant TB to thepopulacedue to incomplete treatment.
Description
Programme & Book of Abstracts for the 7th Annual Research Conference & Fair presented at the Multipurpose Hall, University of Lagos, Akoka on 19th October, 2011
Keywords
Tuberculosis (TB) , HIV , Infection , Lagos University TeachingHospital(LUTH)
Citation
Aderemi-Williams, R.I. Ajamu, I.J. (2011). A Retrospective study on the treatment of adult tuberculosis in Lagos University Teaching Hospital. Programme & Book of Abstracts for the 7th Annual Research Conference & Fair. 98p.