Ectopic pregnancy at the Lagos University Teaching Hospital, Lagos, South-Western Nigeria: Temporal trends, clinical presentation and management outcomes from 2005 to 2014

dc.contributor.authorOlamijulo, JA
dc.contributor.authorOkusanya, BO
dc.contributor.authorAdenekan, MA
dc.contributor.authorUgwu, AO
dc.contributor.authorOlorunfemi, G
dc.contributor.authorOkojie, OO
dc.date.accessioned2022-01-22T16:35:44Z
dc.date.available2022-01-22T16:35:44Z
dc.date.issued2020
dc.description.abstractBackground: There is uncertainty in the trend of ectopic pregnancy incidence in the Southwest region, though the region has a lower fertility rate and a higher contraceptive use than some other regions of Nigeria. The study objective was to determine the temporal trends, presentation and management outcome of ectopic pregnancy at the Lagos University Teaching Hospital (LUTH), Lagos, South-Western Nigeria over a decade. Subjects and Methods: This is a retrospective study of ectopic pregnancies at LUTH, Lagos, Nigeria, from January 2005 to December 2014. Participants’ medical records were used to extract socio-demographic, clinical characteristics, management and outcome data. Joinpoint regression modelling (version 4.7.1) was used to evaluate the trends while descriptive statistics were conducted using Stata version 14 software. Results: There were 434 cases of ectopic pregnancies giving an overall incidence of 2.2/100 deliveries and 3.50/100 gynaecological admissions. Overall, there was a 59.7% increase in the ectopic pregnancy rate from 1.81/100 deliveries in 2005 to 2.89/100 deliveries in 2014. Join point regression revealed two trends. There was an initial non‐significant decrease in incidence of ectopic pregnancy from 2005 to 2010 (annual percent change [APC] = ‐1.5%, 95% confidence interval [CI]: ‐8.1% to 5.6%, P = 0.6). However, there was a statistically significant increase in incidence of ectopic pregnancy at an average of 11.6% per annum from 8.6/100 deliveries in 2011 to 25.4/100 deliveries in 2014 (APC = 11.6%, 95% CI: 1.2% to 23.1% P < 0.001). About one-third (33.9%) of the patients with ectopic pregnancy were within the age range 25–29 years while the majority (68.0%) presented at 9–10 weeks of gestational age. The most common identifiable risk factor was previous pelvic infection (35.71%). Majority (96.5%) had tubal pregnancy and all the cases had laparotomy. There were six maternal deaths giving a case fatality rate of 1.4%. Conclusion: The hospital had an increased trend in the incidence of ectopic pregnancy from 2005 to 2014. Frontline health workers need high index of suspicion in the prompt diagnosis and intervention of ectopic pregnancy among women in the reproductive age.en_US
dc.identifier.citationOlamijulo, Joseph Ayodeji, Babasola Oluwatomi Okusanya, Muisi Alli Adenekan, Aloy Okechukwu Ugwu, Gbenga Olorunfemi, and Osemen Okojie. "Ectopic pregnancy at the Lagos University Teaching Hospital, Lagos, South-Western Nigeria: Temporal trends, clinical presentation and management outcomes from 2005 to 2014." Nigerian Postgraduate Medical Journal 27, no. 3 (2020): 177.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/10683
dc.language.isoenen_US
dc.subjectEctopic pregnancy, extra-uterine gestation, join point regression, maternal mortality, maternal near-miss, temporal trendsen_US
dc.titleEctopic pregnancy at the Lagos University Teaching Hospital, Lagos, South-Western Nigeria: Temporal trends, clinical presentation and management outcomes from 2005 to 2014en_US
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