Evaluation of Baylis–Hillman Routes to 3-(Aminomethyl)coumarin Derivatives

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Date
2013-10-29
Authors
Olasupo, I.
Rose, N.R.
Klein, R.
Adams, L.A.
Familoni, O.B.
Kaye, P.T.
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor & Francis Online
Abstract
The relative merits of two different Baylis–Hillman approaches toward the preparation of coumarin derivatives, containing peptide-like side chains, have been explored. In one approach, use of methyl acrylate as the activated alkene requires a protecting group strategy, an approach that is not necessary when using tert-butyl acrylate.
Description
Staff publications
Keywords
Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry::Organic synthesis , 3-(Aminomethyl)coumarins , aza-Michael , Baylis-Hillman
Citation
Olasupo, I., [Et...al] (2014). Evaluation of Baylis–Hillman Routes to 3-(Aminomethyl) coumarin Derivatives. Synthetic Communications, Vol.44(2), 251-258pp.