Directed metalation of pyridinesulphonamides. Synthesis of pyridine‐fused isothiazoles and 1,2‐oxathioles
| dc.contributor.author | Alo, B.I | |
| dc.contributor.author | Familoni, O.B. | |
| dc.contributor.author | Marsais, F. | |
| dc.contributor.author | Queguiner, G. | |
| dc.date.accessioned | 2019-08-29T13:36:03Z | |
| dc.date.available | 2019-08-29T13:36:03Z | |
| dc.date.issued | 1992-02 | |
| dc.description | Staff Publication | en_US |
| dc.description.abstract | 4‐Lithio‐N‐t‐butylpyridine‐3‐sulphonamide reacted with benzophenone and carbon dioxide respectively to give the corresponding intermediates which on appropriate treatment gave isothiazolo[5,4‐c]pyridin‐3‐one 1,1‐dioxides. Metalation of 2‐ and 4‐(N,N‐dialkylaminosulphonyl)pyridines with lithium diisopropylamide (LDA) gave anions which reacted with benzophenone to give carbinols which thermally cyclised to 1,2‐oxathiolo[3,4‐b]pyridine and 1,2‐oxathiolo[4,3‐c]pyridine respectively. | en_US |
| dc.identifier.citation | Alo, B. I., Familoni, O. B., Marsais, F., & Queguiner, G. (1992). Directed metalation of pyridinesulphonamides. Synthesis of pyridine‐fused isothiazoles and 1, 2‐oxathioles. Journal of heterocyclic chemistry, 29(1), 61-64. | en_US |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/4883 | |
| dc.language.iso | en | en_US |
| dc.publisher | Wiley | en_US |
| dc.relation.ispartofseries | Journal of heterocyclic chemistry;Vol.29(1) | |
| dc.subject | Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry::Organic synthesis | en_US |
| dc.subject | Benzophenone | en_US |
| dc.subject | Carbon dioxide | en_US |
| dc.subject | Carbinols | en_US |
| dc.title | Directed metalation of pyridinesulphonamides. Synthesis of pyridine‐fused isothiazoles and 1,2‐oxathioles | en_US |
| dc.type | Article | en_US |